Abstract: A fastener attached to a first member releasably connects the first member to a second member. The fastener can have a head that moves towards or away from a housing that is separate from, or part of, the first member. A linkage assembly has linkage arm(s) extending from the head to the housing, or to the first member, and the fastener can be pivotally connected at a first end to the housing, or to the first member, and also to the head at a second end. Each linkage arm can define a joint located between the first and second ends. When unfastened, the head can be positioned away from the housing, extending each linkage arm. When fastened, the head may be positioned towards the housing, whereby the joint of each linkage arm can become displaced laterally in the fastener, e.g., connecting the second member to the first member.

Abstract: Device methods and systems for ablating a mucosal surface to treat patients with mucin hypersecretion is disclosed. An ablation device having a balloon membrane with a plurality of electrodes arranged on an external surface thereof is disclosed. The ablation device may be configured to ablate epithelial tissue of one or more target structures, such as the inner wall of a gallbladder. Each of the plurality of electrodes may be electrically coupled to a controller configured to selectively activate one or more of the plurality of electrodes at a time. The controller may activate less than all of the plurality of electrodes, thereby implementing a partial ablation procedure.