Abstract: A computer-implemented method for quantifying arterial stiffness and assigning an AS factor uses executable program on a computing device. The arterial pulse of an individual is monitored and the data received from the monitoring member transmitted to the computing device. The data received is processed by the processor, performing a pulse wave analysis. The primary systolic pulse and iliac reflection pulse are extracted from the pulse wave analysis and the time delay between the primary systolic pulse and the iliac reflection pulse determined. The time delay is used to calculate a second derivative based least in part, on the time delay. The frequency above zero components are separated from the second derivative and the area of the second derivative determined between a first primary systolic pulse and a first iliac reflection pulse.

Abstract: A system for detecting dehydration, hemorrhaging, and increases in blood volume comprising monitors the time difference between the arrival of the primary left ventricular ejection pulse (pulse T1) and the arrival of the iliac reflection (pulse T3) to determine an arterial pulse parameter which is the time difference between T1 T3. Changes in T3 minus T1 are indicative of something happening to blood volume. If the T1-3 value goes up and the patient is on an infusion system, it can be an indication of having too much fluid pumped and if T1-3 is lower than it should be for an individual, they are either dehydrated (which can result in decreases in blood volume), they are hemorrhaging, or they have hemorrhaged. A downtrend in T13 can tell whether someone is continuing to hemorrhage.

Abstract: Blood pressure determination with resolution sufficient to resolve Pulsus Paradoxus is based on measurement of delay time between points on a heartbeat pulse.

Abstract: A fiberoptic sensing apparatus comprises a fiberoptic coupler in which a plurality of optical fibers are joined through a fused coupling region, the optical fibers including at least one input optical fiber and a plurality of output optical fibers, the fiberoptic coupler distributing light incident to the input optical fiber among the plurality of output optical fibers. The coupler is mounted to a support member and configured such that at least a portion of the coupling region can be deflected to change the light distribution among the output fibers without putting the coupling region under tension. A fluid column is cooperative with a deflection member disposed to deflect the portion of the coupling region.

Abstract: A variable coupler fiberoptic sensor utilizes a coupler having a fused coupling region that can be deflected to change the light distribution to a plurality of output fibers without putting the coupling region under tension. A compact, rugged, and highly sensitive sensor design is achieved by use of a coupler having a fused coupling region arranged substantially in a U-shape to allow the input and output fiberoptic leads to extend from the same side of the sensor structure.

Abstract: In a method of measuring pulse transit time of a living subject, first and second pulse wave signals are produced by sensing the pulse at first and second pulse points, respectively, the first and second pulse points being spaced from one another. The first and second pulse wave signals are differentiated, and based on the results, corresponding points of the first and second pulse wave signals are selected (e.g., points of maximum slope). The time delay between the selected points is determined, thus yielding the pulse transit time. A preferred apparatus measures pulse transit time using at least one fiberoptic pulse sensor including a fused-fiber coupling region having at least a portion that can be deflected without putting the coupling region under tension.

Abstract: A sensing pad assembly for monitoring acoustic activity or motion of an object supported on the pad utilizes an improved fiberoptic sensor as a pressure transducing element to convert pressure fluctuations due to the acoustic activity or motion to an output that changes in accordance with the pressure fluctuations. The sensor has an improved design that permits deflection of the coupler fusion region without accompanying tension. In a preferred embodiment, the coupler fusion region is arranged substantially in a U-shape so that the fiberoptic leads of the sensor may be located adjacent to each other at one side of the sensor.

Abstract: In a method of measuring pulse transit time of a living subject, first and second pulse wave signals are produced by sensing the pulse at first and second pulse points, respectively, the first and second pulse points being spaced from one another. The first and second pulse wave signals are differentiated, and based on the results, corresponding points of the first and second pulse wave signals are selected (e.g., points of maximum slope). The time delay between the selected points is determined, thus yielding the pulse transit time. A preferred apparatus measures pulse transit time using at least one fiberoptic pulse sensor including a fused-fiber coupling region having at least a portion that can be deflected without putting the coupling region under tension.

Abstract: The invention relates broadly to a fiber optic sensor device, advantageously, a refractive index measurement device. A light emitting member transmits light, preferably coherent light, to a light splitter. The light splitter splits the light into a first portion that is transmitted to a first fiber optic coupler having an input optical fiber member and an optical fiber member having a waist region. A first output optical fiber member emerges from the first fiber optic coupler waist region. The light splitter is positioned to insert light into the first fiber optic coupler input optical fiber member. A reference fiber optic coupler includes an input optical fiber member and an optical fiber member having a waist region. The reference fiber optic coupler is enclosed in a potting medium stable reference of constant refractive index. A reference output optical fiber member emerges from the reference fiber optic coupler waist region.

Abstract: A variable coupler fiberoptic sensor utilizes a coupler having a fused coupling region that can be deflected to change the light distribution to a plurality of output fibers without putting the coupling region under tension. A compact, rugged, and highly sensitive sensor design is achieved by use of a coupler having a fused coupling region arranged substantially in a U-shape to allow the input and output fiberoptic leads to extend from the same side of the sensor structure.