Patents Assigned to EMSTOPA LIMITED
  • Publication number: 20260042863
    Abstract: The present invention provides tissue plasminogen activator antibody molecules and their uses. More particularly, the presently-disclosed invention provides humanised antibody molecules which specifically bind tissue plasminogen activator (TPA) and their use in treating TPA induced haemorrhage, in particular treating systemic haemorrhage such as brain haemorrhage after treatment of ischemic stroke or myocardial infarction, or systemic bleeding after TPA treatment of pulmonary embolism, ischemic stroke or myocardial infarction.
    Type: Application
    Filed: July 17, 2025
    Publication date: February 12, 2026
    Applicant: EMSTOPA LIMITED
    Inventors: James Carl KEITH, JR., Alexander Noel Fraser BROWN, Preeti BAKRANIA
  • Patent number: 12486333
    Abstract: The present invention provides tissue plasminogen activator antibody molecules and their uses. More particularly, the presently-disclosed invention provides humanised antibody molecules which specifically bind tissue plasminogen activator (TPA) and their use in treating TPA induced haemorrhage, in particular treating systemic haemorrhage such as brain haemorrhage after treatment of ischemic stroke or myocardial infarction, or systemic bleeding after TPA treatment of pulmonary embolism, ischemic stroke or myocardial infarction.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: December 2, 2025
    Assignee: EMSTOPA LIMITED
    Inventors: James Carl Keith, Jr., Alexander Noel Fraser Brown, Preeti Bakrania