Abstract: A clamping device for a shaft of a catheter can include a first member rotatably coupled to a second member. The first member can have an annular element defining a central lumen, the outer surface of the annular element having a non-circular cross-sectional profile, and the second member can define a bore into which the annular element extends, the bore having a non-circular cross-sectional profile. The device can move between a release state wherein the central lumen has a first diameter, and a clamped state wherein the central lumen has a second diameter less than the first diameter. When the clamping device is in the clamped state, the clamping device can engage an outer surface of a catheter shaft and when the clamping device is in the release state, the clamping device can be moved along a length of the catheter shaft.

Abstract: A venous drainage cannula, catheter, or other device is in certain embodiments convertible or adjustable for application in cardiac surgery procedures involving cardiopulmonary bypass. Such a convertible cannula device can be modified, for example, for use as both a multi-stage cannula and a bi-caval cannula, so that the same device can be used in multiple different procedures where one or the other cannula type is needed. Such convertible cannula or other device can simplify and reduce a number of parts needed for a bypass procedure, by providing one adjustable and versatile device to serve multiple functions where different cannulae are traditionally required. Various embodiments further provide cannula devices where a variety of different hole or opening arrangements and configurations can be achieved, to adapt to various different procedures.