Patents Assigned to EnBIO Limited
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Publication number: 20220170163Abstract: A metal surface treatment method wherein the surface (10) is simultaneously bombarded with a mixture of abrasive particles (4) and dopant particles (6) which are delivered at a velocity in the range of 50-250 m/sec, and thereby depositing the dopant material on the surface. Also provided is an article (8) having a surface treated by such a method.Type: ApplicationFiled: July 9, 2021Publication date: June 2, 2022Applicant: ENBIO LIMITEDInventors: Barry TWOMEY, John O'DONOGHUE, Kevin ROCHE, Liam O'NEILL, Paolo Vincenzo Ercole FIORINI
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Patent number: 9695505Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: GrantFiled: December 15, 2015Date of Patent: July 4, 2017Assignee: ENBIO LIMITEDInventors: John Gerard O'Donoghue, Donncha Haverty
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Patent number: 9242268Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: GrantFiled: February 2, 2015Date of Patent: January 26, 2016Assignee: EnBio LimitedInventors: John Gerard O'Donoghue, Donncha Haverty
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Patent number: 9034422Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: GrantFiled: October 17, 2014Date of Patent: May 19, 2015Assignee: EnBio LimitedInventors: John Gerard O'Donoghue, Donncha Haverty
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Patent number: 8889212Abstract: The present invention relates to a method of treating an article surface. The method includes removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles including a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also includes delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: GrantFiled: November 30, 2011Date of Patent: November 18, 2014Assignee: EnBio LimitedInventors: John Gerard O'Donoghue, Donncha Haverty
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Patent number: 8771782Abstract: The present invention is directed to methods for producing a coated substrate, including dissolving at least one biomolecule to form a solution; nebulizing the solution to form a liquid aerosol; combining the liquid aerosol and a plasma to form a coating; and depositing, in the absence of reactive monomers, the coating onto a substrate surface. In an aspect, the substrate can be an implantable medical device.Type: GrantFiled: December 9, 2011Date of Patent: July 8, 2014Assignee: Enbio LimitedInventors: Liam O'Neill, John O'Donoghue, Joe O'Keeffe, Peter Dobbyn
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Patent number: 8765211Abstract: Disclosed herein are methods of treating an article surface. The method comprises delivering a polymer and drug to a medical implant having a porous surface and using at least one particle stream from at least one fluid jet to subsequently remove the polymer from the outer surface of the metal substrate, thereby retaining the therapeutic agent and polymer within the pores of the implant.Type: GrantFiled: March 31, 2010Date of Patent: July 1, 2014Assignee: Enbio LimitedInventors: Liam O'Neill, Caroline O'Sullivan
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Publication number: 20120171354Abstract: The present invention is directed to methods for producing a coated substrate, including dissolving at least one biomolecule to form a solution; nebulizing the solution to form a liquid aerosol; combining the liquid aerosol and a plasma to form a coating; and depositing, in the absence of reactive monomers, the coating onto a substrate surface. In an aspect, the substrate can be an implantable medical device.Type: ApplicationFiled: December 9, 2011Publication date: July 5, 2012Applicant: EnBIO LimitedInventors: Liam O'Neill, John O'Donoghue
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Publication number: 20120135133Abstract: Disclosed herein are methods of treating an article surface. The method comprises delivering a polymer and drug to a medical implant having a porous surface and using at least one particle stream from at least one fluid jet to subsequently remove the polymer from the outer surface of the metal substrate, thereby retaining the therapeutic agent and polymer within the pores of the implant.Type: ApplicationFiled: March 31, 2010Publication date: May 31, 2012Applicant: ENBIO LIMITEDInventors: Liam O'Neill, Caroline O'Sullivan
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Publication number: 20120114830Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: ApplicationFiled: November 30, 2011Publication date: May 10, 2012Applicant: EnBIO LimitedInventors: John Gerard O'Donoghue, Donncha Haverty
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Patent number: 8119183Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: GrantFiled: September 11, 2007Date of Patent: February 21, 2012Assignee: EnBIO LimitedInventors: John Gerard O'Donoghue, Donncha Haverty
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Publication number: 20110104991Abstract: Disclosed herein are nozzle configurations for an abrasive blasting system. The system can comprise multiple hoppers for feeding separate powders streams to a fluid jet. The separate powder streams can be mixed in a frustoconical or conical mixer prior to delivery to the substrate surface. Also disclosed are methods of texturizing the substrate surface by moving the substrate or nozzle(s) during the delivery of dopant(s). Methods for achieving a uniform distribution of dopant are also described. Also disclosed herein are coaxial nozzle configurations having an outer focusing stream to converge and/or mix with an inner particle stream.Type: ApplicationFiled: March 11, 2009Publication date: May 5, 2011Applicant: ENBIO LIMITEDInventors: John Gerard O'Donoghue, Leo Sexton
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Publication number: 20110081399Abstract: Disclosed herein are methods of modifying a nitinol surface by using abrasive blasting techniques. The surface modification can be performed by abrasively blasting the surface and delivering at least one dopant from one or more fluid jets to cause the at least one dopant to impregnate and/or coat the nitinol surface. The nitinol surface can form a portion or all of a medical device, such as an implantable medical device, e.g., a stent.Type: ApplicationFiled: March 13, 2009Publication date: April 7, 2011Applicant: ENBIO LIMITEDInventors: John Gerard O'Donoghue, Peter O'Hare
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Publication number: 20100173569Abstract: Disclosed herein is a containment system for a blasting device to prevent release of resulting particulate material into the environment. The system comprises a blasting device having at least one fluid jet nozzle for delivering a stream of particles under pressure toward a substrate positioned on a supporting platform. The containment is a plastic, flexible container having openings penetrated by the at least one fluid jet nozzle and supporting platform. The openings are sealably attached to the blasting device to isolate the interior of the container and the device from the outer environment.Type: ApplicationFiled: January 7, 2009Publication date: July 8, 2010Applicant: ENBIO LIMITEDInventors: Liam O'Neill, Leo Sexton
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Publication number: 20080274671Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: ApplicationFiled: September 11, 2007Publication date: November 6, 2008Applicant: ENBIO LIMITEDInventors: John Gerard O'Donoghue, Donncha Haverty
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Patent number: RE45877Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.Type: GrantFiled: December 31, 2014Date of Patent: February 2, 2016Assignee: EnBio LimitedInventors: John Gerard O'Donoghue, Donncha Haverty