Abstract: Provided herein are compositions and methods for selective expression of a transgene. Compositions and methods for selective expression of a transgene comprise one or more human regulatory elements, which, when operably linked to a transgene, can facilitate selective expression of a transgene (e.g., cell-type selective expression) in a target cell as compared to at least one or more non-target cells.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
December 31, 2019
Assignee:
Encoded Therapeutics, Inc.
Inventors:
Stephanie Tagliatela, Andrew Young, Szu-Ying Chen, Kartik Ramamoorthi, David Oberkofler
Abstract: Provided herein are compositions and methods for selective expression of a transgene. Compositions and methods for selective expression of a transgene comprise one or more human regulatory elements, which, when operably linked to a transgene, can facilitate selective expression of a transgene (e.g., cell-type selective expression) in a target cell as compared to at least one or more non-target cells.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
May 14, 2019
Assignee:
Encoded Therapeutics, Inc.
Inventors:
Stephanie Tagliatela, Andrew Young, Szu-Ying Chen, Kartik Ramamoorthi, David Oberkofler
Abstract: Provided herein are compositions and methods for selective expression of a transgene. Compositions and methods for selective expression of a transgene comprise one or more human regulatory elements, which, when operably linked to a transgene, can facilitate selective expression of a transgene (e.g., cell-type selective expression) in a target cell as compared to at least one or more non-target cells.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
May 14, 2019
Assignee:
Encoded Therapeutics, Inc.
Inventors:
Stephanie Tagliatela, Andrew Young, Szu-Ying Chen, Kartik Ramamoorthi, David Oberkofler