Patents Assigned to Endece, LLC
  • 6-substituted estradiol derivatives and methods of use
    Patent number: 8629130
    Abstract: A method of inhibiting growth of cancer cells comprising contacting cancer cells with a 6-substituted estradiol derivative in an amount at least partially sufficient to inhibit said growth is disclosed. The compounds have the general formula depicted below, herein R1, R2, R3, R4, R5, R6 and R7 are as defined herein.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: January 14, 2014
    Assignee: Endece, LLC
    Inventor: James G. Yarger
  • 6-substituted estradiol derivatives and methods of use
    Patent number: 8168621
    Abstract: A compound having the structure: wherein R1, R2, R, R, X, Y and Z are as defined herein. The compounds are estrogen receptor modulators useful for the treatment of proliferative disorders.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: May 1, 2012
    Assignee: Endece, LLC
    Inventor: James Yarger
  • Exemestane compounds, compositions and related methods of use
    Patent number: 7846918
    Abstract: 6-Methyloxaalkyl exemestane compounds and related compositions, as can be used, chemotherapeutically, to inhibit growth and proliferation of cancer cells.
    Type: Grant
    Filed: October 2, 2006
    Date of Patent: December 7, 2010
    Assignee: Endece, LLC
    Inventors: Richard J. Pariza, James G. Yarger