Patents Assigned to Endogen, Inc.
  • Method of evaluating immune system response to allografts, viral infection and immunosuppressive therapy
    Patent number: 4959302
    Abstract: Detection of solublen Interleukin-2 (IL-2) and Interleukin-2 receptor (IL-2R) levels in the serum, plasma, urine and bile of kidney and liver transplant patients using sensitive immunoassays provides valuable prognostic, monitoring and diagnostic information about impending, acute and chronic or recovering allograft rejection episodes. Additionally, monitoring immune system activation with these sensitive immunoassays can be useful for detecting viral and other infections and for distinguishing cyclosporine toxicity from graft rejection.
    Type: Grant
    Filed: August 20, 1987
    Date of Patent: September 25, 1990
    Assignee: Endogen, Inc.
    Inventors: Andrew J. Cornaby, Roy A. Dempsey