Abstract: The present invention provides a dry powder that is suitable for use in forming a hydrogel and characterized by a stable composition at ambient conditions. The dry powder includes a prepolymer including a straight chain polyethylene glycol, and a thermally activated free radical initiator selected from the group consisting of sodium persulfate, potassium persulfate, and ammonium persulfate. The present invention also provides a method of forming the dry powder, and a method of preparing a hydrogel where a reaction mixture is formed including the dry powder and a buffered aqueous solution.

Abstract: A system includes an inner filling structure around a stent-structure and an outer filling structure around the inner filling structure. The inner filling structure can be configured to produce a proximal seal with a first portion of an artery at a proximal end and a distal seal with a second portion of an artery at a distal end when the inner filling structure is in an inflacted state. The outer filling structure can have an inner surface surrounding at least a portion of the inner filling structure. The outer filling structure can be configured to be inflatable to occupy a space within an aneurysm at a lower pressure than a pressure in the inner filling structure.

Abstract: A system includes a filling structure deployable at least partially in a common iliac artery and an external iliac artery, and a scaffold positioned within a first lumen of the filling structure. The scaffold has a fenestration in a side of the scaffold that is positionable toward an internal iliac artery. The filling structure has a second lumen extending from the first lumen and positionable toward the internal iliac artery. A method includes deploying a filling structure at least partially in a common iliac artery and an external iliac artery and positioning a scaffold within a lumen of the filling structure such that a fenestration in a side of the scaffold is positioned toward an internal iliac artery.

Abstract: Some embodiments are directed to a stent graft comprising a first stent graft having a first and a second stent and a first and a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.