Abstract: Provided herein are peptides that bind ?-catenin, and compositions comprising said peptides. Peptides binding ?-catenin prevent translocation to the nucleus and modulate the canonical Wnt pathway. Also provided herein are methods of using said peptides and compositions in the treatment of tissue-infiltrating conditions including endometriosis.
Type:
Grant
Filed:
November 21, 2019
Date of Patent:
January 30, 2024
Assignee:
EndoMet Biosciences, Inc.
Inventors:
Tanya Petrossian, Stephen Fiacco, Tristin Rose, Amanda Hardy, Keerthi Boddupally, Matthew Willmore