Patents Assigned to Endostim, Inc.
-
Publication number: 20140249594Abstract: The present specification discloses devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: ApplicationFiled: March 7, 2014Publication date: September 4, 2014Applicant: EndoStim, Inc.Inventors: Virender K. Sharma, Matt Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kaila Raby
-
Publication number: 20140243593Abstract: An implantable electrical stimulation lead for the treatment of biological conditions includes a lead body with an electrical connector at one end and a pair of monopolar branches at the other end. The lead body has a length ranging from 390 mm to 490 mm to allow for implantation from an incision site further removed from the final positioning site of the electrodes. The branches have lengths ranging from 50 mm to 120 mm for the both branches. These lengths facilitate successful laparoscopic implantation at sites with confined anatomy, such as, near the gastroesophageal junction. The branches include needles and sutures at their ends for suturing anchors positioned on the branches to surrounding tissue. The needles have curves designed to facilitate maneuvering in confined anatomy. A separate lead includes a suture loop connecting the ends of the first and second branches rather than needles. The loop is used to pull the lead through the working channel of an endoscope.Type: ApplicationFiled: February 26, 2014Publication date: August 28, 2014Applicant: EndoStim, Inc.Inventors: Paul V. Goode, Ofer Glasberg, Virender K. Sharma
-
Publication number: 20140228911Abstract: The present specification discloses devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: ApplicationFiled: March 7, 2014Publication date: August 14, 2014Applicant: EndoStim, Inc.Inventors: Virender K. Sharma, Matt Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kaila Raby
-
Publication number: 20140222106Abstract: The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: ApplicationFiled: February 7, 2014Publication date: August 7, 2014Applicant: EndoStim, Inc.Inventors: Virender K. Sharma, Matt Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kaila Raby
-
Patent number: 8798753Abstract: An implantable stimulation device for use in stimulation based treatments for diseases such as GERD or obesity is described. The device is provided with an anchoring unit which upon deployment assumes a shape optimized for the site of deployment. Sensing electrodes and stimulating electrodes in the device are also designed to assume a suitable shape upon deployment. A novel catheter is also provided for easy and expeditious deployment of the device.Type: GrantFiled: July 2, 2013Date of Patent: August 5, 2014Assignee: EndoStim, Inc.Inventor: Virender K. Sharma
-
Patent number: 8712530Abstract: The present specification discloses devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: GrantFiled: March 4, 2011Date of Patent: April 29, 2014Assignee: EndoStim, Inc.Inventors: Virender K. Sharma, Matthew Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kaila Raby
-
Patent number: 8712529Abstract: The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: GrantFiled: March 4, 2011Date of Patent: April 29, 2014Assignee: EndoStim, Inc.Inventors: Virender K. Sharma, Matthew Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kaila Raby
-
Publication number: 20140088664Abstract: The present specification discloses devices and methodologies for the treatment of achalasia. Individuals with achalasia are treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: ApplicationFiled: August 23, 2013Publication date: March 27, 2014Applicant: Endostim, Inc.Inventors: Virender K. Sharma, Shai Policker, Bevil Hogg
-
Publication number: 20140018657Abstract: An implantable stimulation device for use in stimulation based treatments for diseases such as GERD or obesity is described. The device is provided with an anchoring unit which upon deployment assumes a shape optimized for the site of deployment. Sensing electrodes and stimulating electrodes in the device are also designed to assume a suitable shape upon deployment. A novel catheter is also provided for easy and expeditious deployment of the device.Type: ApplicationFiled: July 2, 2013Publication date: January 16, 2014Applicant: Endostim, Inc.Inventor: Virender K. Sharma
-
Patent number: 8543210Abstract: An implantable stimulation device for use in stimulation based treatments for diseases such as GERD or obesity is described. The device is provided with an anchoring unit which upon deployment assumes a shape optimized for the site of deployment. Sensing electrodes and stimulating electrodes in the device are also designed to assume a suitable shape upon deployment. A novel catheter is also provided for easy and expeditious deployment of the device.Type: GrantFiled: January 25, 2009Date of Patent: September 24, 2013Assignee: Endostim, Inc.Inventor: Virender K. Sharma
-
Patent number: 8538534Abstract: The present specification describes methods and devices using electrical stimulation to modulate lower esophageal sphincter (LES) pressure. The electrical stimulation may be delivered to the LES via one or more electrodes that is placed in contact with the LES tissue. The methods and devices are useful to treat a number of conditions or disease conditions, including for example, gastroesophageal reflux disease (GERD).Type: GrantFiled: March 13, 2012Date of Patent: September 17, 2013Assignee: Endostim, Inc.Inventors: Edy E. Soffer, Jeffrey Conklin
-
Publication number: 20130178912Abstract: The specification discloses methods and devices for electrically stimulating one or more structures in the gastrointestinal tract. The one or more structures are preferably selected from the upper esophageal sphincter, the esophagus and gastric fundus. The method may involve the step of arranging a plurality of stimulating electrodes adjacent one or more structures which may further include the lower esophageal sphincter, the stomach, the pyloric sphincter, the small intestine, the colon and the vagus. The method and device may further include sensing electrodes to detect change in one or more physiological parameters in the gastrointestinal tract and modulate the stimulating electrodes in response to the change. The device comprises a pulse generator, a power source, a plurality of stimulating electrode set, one or more sensing electrodes and means for varying activity of the stimulating electrodes in response to change detected in the gastrointestinal tract.Type: ApplicationFiled: October 26, 2012Publication date: July 11, 2013Applicant: Endostim, Inc.Inventor: Endostim, Inc.
-
Patent number: 8447404Abstract: The present specification discloses devices and methodologies for the treatment of diurnal GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: GrantFiled: March 4, 2011Date of Patent: May 21, 2013Assignee: Endostim, Inc.Inventors: Virender K. Sharma, Matthew Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kalia Raby
-
Patent number: 8447403Abstract: The present specification discloses devices and methodologies for the treatment of nocturnal GERD. Individuals with nocturnal GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.Type: GrantFiled: March 4, 2011Date of Patent: May 21, 2013Assignee: Endostim, Inc.Inventors: Virender K. Sharma, Matthew Joseph Gani, Paul V. Goode, Bevil Hogg, Jay Miazga, Shai Policker, Kaila Raby
-
Publication number: 20130035740Abstract: The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow, have improved energy storage requirements, enable improved LES function while concurrently delivering additional health benefits, and enable improved LES function post stimulation termination.Type: ApplicationFiled: May 3, 2012Publication date: February 7, 2013Applicant: Endostim, Inc.Inventors: Virender K. Sharma, Edy Sofer, Paul V. Goode, Bevil Hogg, Shai Policker, Matthew Joseph Gani, Jay Miazga, Kaila Raby
-
Patent number: 8160709Abstract: The present invention describes methods and devices using low frequency electrical stimulation or neural high frequency stimulation to modulate lower esophageal sphincter (LES) pressure. The electrical stimulation may be delivered to the LES via one or more electrodes that is placed in contact with the LES tissue. The methods and devices are useful to treat a number of conditions or disease conditions, including for example, gastroesophageal reflux disease (GERD).Type: GrantFiled: May 14, 2007Date of Patent: April 17, 2012Assignee: Endostim, Inc.Inventors: Edy E. Soffer, Jeffrey Conklin
-
Patent number: 7738961Abstract: A method and device for electrically stimulating one or more structures in the gastrointestinal tract as described. The one or more structures are preferably selected from the upper esophageal sphincter, the esophagus and gastric fundus. The method may involve the step of arranging a plurality of stimulating electrodes adjacent one or more structures which may further include the lower esophageal sphincter, the stomach, the pyloric sphincter, the small intestine, the colon and the vagus. The method and device may further include sensing electrodes to detect change in one or more physiological parameters in the gastrointestinal tract and modulate the stimulating electrodes in response to the change. The device comprises a pulse generator, a power source, a plurality of stimulating electrode set, one or more sensing electrodes and means for varying activity of the stimulating electrodes in response to change detected in the gastrointestinal tract. The method and device may be used to treat obesity and/or GERD.Type: GrantFiled: October 9, 2006Date of Patent: June 15, 2010Assignee: Endostim, Inc.Inventor: Virender K Sharma