Abstract: Novel intermediates for the complete synthesis of vitamin D are provided that allow a great versatility of functional groups in the final vitamin derivatives. Vitamin derivatives that are epimeric in position 3 and vitamin derivatives with a wide range of functionalities in position 18, including compounds with isotopic labelling are provided.
Type:
Grant
Filed:
December 9, 2013
Date of Patent:
June 12, 2018
Assignee:
Endotherm GmbH
Inventors:
Borja Lopez Perez, Rita Sigueiro Ponte, Miguel A. Maestro Saavedra, Antonio Mourino Mosquera