Abstract: A recombinant protein having bacteriophage endosialidase enzymatic activity obtainable by expression from a recombinant vector comprising a DNA sequence encoding a bacteriophage endosialidase linked to a DNA sequence of an expression vector which express a polypeptide which adds to the N-terminus of the endosialidase, or an analogue of said protein, which is a mutant, functional fragment or derivative of said protein having endosialidase enzymatic activity.
Type:
Grant
Filed:
April 2, 1998
Date of Patent:
December 18, 2001
Assignee:
Endozyme Limited
Inventors:
Peter William Taylor, John Paul Luzio, Jonathan Mark Bryant