Patents Assigned to EnhancedBio Inc.
  • Ionizable lipid compounds, lipid nanoparticles comprising same and therapeutic uses thereof
    Patent number: 11911485
    Abstract: The present invention relates to lipid nanoparticles for in vivo drug delivery and uses thereof, and the lipid nanoparticle are liver tissue-specific, have excellent biocompatibility and can deliver a gene therapeutic agent with high efficiency, and thus it can be usefully used in related technical fields such as lipid nanoparticle mediated gene therapy.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: February 27, 2024
    Assignee: EnhancedBio Inc.
    Inventors: Hyukjin Lee, Minjeong Kim, Hansaem Jeong, Hyokyoung Kwon, Yunmi Seo, Michaela Jeong
  • Enhancing radiation sensitivity comprising administering PMVK inhibiting siRNA and shRNA
    Patent number: 11674184
    Abstract: The present invention relates to a biomarker composition for diagnosing radiation-resistant cancer comprising PMVK as an active ingredient and a method of diagnosing radiation-resistant cancer using the same, and when the PMVK is knocked down, it is confirmed that the survival rate of cancer cells decreases during radiation treatment, and based on this, the possibility as a factor related to radiation therapy resistance to cancer was suggested, and the PMVK can be used as a new target to enhance the effect of radiation therapy on human cancer cells.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: June 13, 2023
    Assignee: ENHANCEDBIO INC.
    Inventors: Eun Kyung Choi, Seong-Yun Jeong, Si Yeol Song, Yun-Yong Park, Seok Soon Park, Eun Jin Ju, Eun Jung Ko
  • Lipid nanoparticles for in-vivo drug delivery, and uses thereof
    Patent number: 11464870
    Abstract: The present invention relates to lipid nanoparticles for in vivo drug delivery and uses thereof, and the lipid nanoparticle are liver tissue-specific, have excellent biocompatibility and can deliver a gene therapeutic agent with high efficiency, and thus it can be usefully used in related technical fields such as lipid nanoparticle mediated gene therapy.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: October 11, 2022
    Assignee: ENHANCEDBIO INC.
    Inventors: Hyukjin Lee, Minjeong Kim, Hansaem Jeong, Hyokyoung Kwon, Yunmi Seo, Michaela Jeong
  • BIOMARKER COMPOSITION FOR DIAGNOSING RADIATION-RESISTANT CANCER OR FOR PREDICTING PROGNOSIS OF RADIATION THERAPY CONTAINING PMVK AS ACTIVE INGREDIENT
    Publication number: 20210025007
    Abstract: The present invention relates to a biomarker composition for diagnosing radiation-resistant cancer comprising PMVK as an active ingredient and a method of diagnosing radiation-resistant cancer using the same, and when the PMVK is knocked down, it is confirmed that the survival rate of cancer cells decreases during radiation treatment, and based on this, the possibility as a factor related to radiation therapy resistance to cancer was suggested, and the PMVK can be used as a new target to enhance the effect of radiation therapy on human cancer cells.
    Type: Application
    Filed: November 21, 2018
    Publication date: January 28, 2021
    Applicant: ENHANCEDBIO INC.
    Inventors: Eun Kyung CHOI, Seong-Yun JEONG, Si Yeol SONG, Yun-Yong PARK, Seok Soon PARK, Eun Jin JU, Eun Jung KO
  • Composition for treating cancer associated with HPV infection
    Patent number: 10221418
    Abstract: The present invention relates to a composition for preventing or treating diseases associated with human papillomavirus (HPV), and more specifically, cancer associated with HPV, and even more specifically, cervical cancer. The nucleotide sequence of the present invention, the sequence in which the base thereof is modified, and a specific combination thereof can be useful in a composition for effectively treating diseases associated with HPV infection by greatly inhibiting the expression of the E6/E7 gene of HPV type 16 or 18.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: March 5, 2019
    Assignee: EnhancedBio Inc.
    Inventors: Young Kee Shin, Young Deug Kim, Hun Soon Jung, Deuk Ae Kim