Patents Assigned to Enobia Pharma
  • Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX
    Patent number: 7365091
    Abstract: The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: April 29, 2008
    Assignee: Enobia Pharma
    Inventors: Denis Gravel, Elaref S. Ratemi, Mostafa Hatam, Guy Boileau, Philippe Crine, Isabelle Lemire
  • Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX
    Publication number: 20060287280
    Abstract: The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.
    Type: Application
    Filed: May 26, 2006
    Publication date: December 21, 2006
    Applicant: Enobia Pharma
    Inventors: Denis Gravel, Elaref Ratemi, Mostafa Hatam, Guy Boileau, Philippe Crine, Isabelle Lemire
  • Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex
    Patent number: 7105539
    Abstract: The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: September 12, 2006
    Assignee: Enobia Pharma
    Inventors: Denis Gravel, Elaref S. Ratemi, Mostafa Hatam, Guy Boileau, Philippe Crine, Isabelle Lemire
  • Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex
    Publication number: 20060135480
    Abstract: The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula (I), useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.
    Type: Application
    Filed: December 3, 2003
    Publication date: June 22, 2006
    Applicant: Enobia Pharma
    Inventors: Denis Gravel, Elaref Ratemi, Mostafa Hatam, Guy Boileau, Philippe Srine, Isabelle Lemire