Patents Assigned to ENS-ECOLE NORMALE SUPERIEURE DE LYON
  • Biofunctionalized nanoparticles and uses thereof in adoptive cell therapy
    Patent number: 10588986
    Abstract: The present invention relates to biofunctionalized nanoparticles and uses thereof in adoptive cell therapy. In particular, the present invention relates to a nanoparticle comprising an amount of at least one antigen and an amount of at least one antibody having specificity for a B cell receptor wherein the antigen and antibody are attached to the surface of the nanoparticle.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: March 17, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ENS-ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD-LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), HOSPICE CIVILS DE LYON
    Inventors: Antoine Sicard, Olivier Thaunat
  • INSULATING POLYNUCLEOTIDES DERIVED FROM ELEMENT D4Z4 AND THEIR USES IN TRANSGENESIS
    Publication number: 20100330675
    Abstract: Polynucleotides with insulating properties allowing protection of the expression of a transgene from adjacent cis elements in higher eukaryotic cells. In particular, these polynucleotides can be used for transgenesis, gene therapy and the production of recombinant proteins.
    Type: Application
    Filed: July 30, 2008
    Publication date: December 30, 2010
    Applicants: ENS - ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
    Inventors: Frederique Magdinier, Eric Gilson, Alexandre Ottaviani, Sylvie Gervier Rival
  • Modified ES cells and ES cell-specific genes
    Publication number: 20090151013
    Abstract: The invention concerns modified avian ES cells, specifically expressing an exogenous gene when they have a pluripotent character. The invention also concerns a nucleic acid and a polypeptide specifically expressed in pluripotent avian cells, and methods for detecting the pluripotent character of cells using said nucleic acid and polypeptide.
    Type: Application
    Filed: November 21, 2007
    Publication date: June 11, 2009
    Applicants: INSTITUT NATIONAL DE LA RESEARCHE AGRONOMIQUE, ENS-ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Herve Acloque, Anne-Marie Birot, Valerie Risson, Bertrand Pain, Jacques Samarut