Abstract: A hand brake device for a wheelchair comprising a hand brake device on either handlebar and an associated brake provided on wheel. The hand brake device comprises a body member, a brake lever, and an actuator. Brake lever is coupled to brake cable. Body member comprises an open space with two extended opposite curve members of brake lever received therein, and a recess pivoted about a bolt. Operator may grip lever member to pivot brake lever so as to move toward or away from handlebar, thus tautening the brake cable for braking. A stopper member is inserted into channel of opening on the side of body member. When the brake lever is pulled toward or pushed away from the handle, the brake cable is tautened for braking the vehicle such that the stopper member clears from the channel. Further, pulls or pushes the actuator to cause the end of the stopper member to be clung between the dents, thereby locking the vehicle.