Patents Assigned to Enteric Research Laboratories
  • Campylobacter jejuni antigens and methods for their production and use
    Patent number: 5874300
    Abstract: The present invention provides an isolated nucleic acid encoding an approximately 26 kilodalton antigen, PEB1A, of Campylobacter jejuni, or an antigenic fragment thereof, wherein the antigen is associated with diarrheal disease. The present invention also provides methods of detecting the presence of a Campylobacter jejuni strain possessing the PEB1A antigen in a subject. Vaccines and treatments for C. jejuni infection are provided, as is a mutant C. jejuni not expressing a functional PEB1A antigen.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: February 23, 1999
    Assignee: Enteric Research Laboratories
    Inventors: Martin J. Blaser, Zhiheng Pei