Abstract: There is provided an insect model for determining the penetration of nanoparticles through the BBB. The model is also directed to the use of insects for studying the environmental safety of nanoparticles. The particles are administered into the hemolymf of an insect having a BBB, such as the locust, and the uptake into the brain is analysed. Thus, in this model it is possible to investigate the potential up-take into the brain of nanoparticles circulating in the blood.
Type:
Application
Filed:
August 10, 2010
Publication date:
May 17, 2012
Applicant:
ENTOMOPHAM APS
Inventors:
Peter Aadal, Gunnar Andersson, Olga Andersson