Abstract: In a tissue irrigating solution of the type containing the combination of glutathione, bicarbonate, and Ringer solution (GBR), the bicarbonate and glutathione are freeze-dried, packaged and separately stored in lyophilized powder form until just preceding the operation, at which time the lyophilized powder containing the bicarbonate and glutathione is dissolved directly into a conventional I.V. solution.

Abstract: In a tissue irrigating solution of the type containing the combination of glutathione, bicarbonate, and Ringer solution (GBR), the chloride salts (Ringer solution) are packaged and stored in solution and the bicarbonate and glutathione are freeze-dried and packaged and separately stored in powder form until immediately preceeding the operation, at which time the bicarbonate and glutathione are dissolved directly into the solution of chloride salts. The resulting solution is mixed within 24 hours of use.

Abstract: A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before steam sterilizing. The blister packs have Tyvek.TM. lids and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.

Abstract: A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before steam sterilizing. The blister packs have Tyvek.TM. lids and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.

Abstract: In a tissue irrigating solution of the type containing the combination of glutathione, bicarbonate, and Ringer solution (GBR), the chloride salts (Ringer solution) and packaged and stored in solution and the bicarbonate and glutathione are freeze-dried and packaged and separately stored in powder form until immediately preceeding the operation, at which time the bicarbonate and glutathione are dissolved directly into the solution of chloride salts. The resulting solution is mixed within 24 hours of use.

Abstract: A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before steam sterilizing. The blister packs have Tyvek.TM. lids and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.

Abstract: A linking mechanism for irrigation/aspiration machines which includes a coupling member having a plug that is inserted into an opening in a receptacle on the face of the I/A machine. The plug projection is sealed in air tight relation to the wall surrounding the opening and an auxiliary prong(s) prevent rotation of the plug as well as lock the plug in the receptacle. The receptacle includes an arming switch activated responsive to proper seating of the plug in the receptacle to arm the peristaltic pump that is subsequently operated by a foot switch to generate a vacuum in the aspirant line.

Abstract: A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before stream sterilizing. The blister packs have Tyvek.TM. closures and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.

Abstract: A linking mechanism for irrigation/aspiration machines which includes a coupling member having a plug that is inserted into an opening in a receptacle on the face of the I/A machine. The plug projection is sealed in air tight relation to the wall surrounding the opening and an auxiliary prong(s) prevent rotation of the plug as well as lock the plug in the receptacle. The receptacle includes an arming switch activated responsive to proper seating of the plug in the receptacle to arm the peristaltic pump that is subsequently operated by a foot switch to generate a vacuum in the aspirant line.