Abstract: Certain embodiments of the inventive technology may be described as an enclosed, mobile emergency response unit that comprises an enclosure and an underlying support frame on which the enclosure is established, where that enclosure may include a medical compartment that is unsecured when the enclosed, mobile emergency response unit is on operational standby, an onboard equipment compartment that is secured, when the enclosed, mobile emergency response unit is on operational standby, and a ramped, portable equipment compartment that is unsecured when the enclosed, mobile emergency response unit is on operational standby. Embodiments of the inventive technology may further include, e.g., a fire suppression system, a fueled electrical power generator, a compressor, a solar power system, medical equipment, wi-fi provision componentry and/or operational parameter monitors, among other componentry.