Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer and other diseases. Also described herein are methods that can be used to identify modulators of chemokine receptors.
Abstract: Described herein are methods that can be used for diagnosis and prognosis of colorectal cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate colorectal cancer. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in colorectal cancer are described.
Type:
Grant
Filed:
September 6, 2000
Date of Patent:
September 24, 2002
Assignee:
Eos Biotechnology, Inc.
Inventors:
David Mack, Kurt C. Gish, Keith E. Wilson
Abstract: Described herein are methods that can be used for diagnosis and prognosis of prostate cancer and/or breast cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate prostate cancer and/or breast cancer. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in prostate cancer, breast cancer and other cancers are described.
Type:
Application
Filed:
April 30, 2001
Publication date:
June 6, 2002
Applicant:
EOS BIOTECHNOLOGY, INC.
Inventors:
Peter Hevezi, David Mack, Kurt C. Gish, Keith E. Wilson
Abstract: Described herein are methods that can be used for diagnosis and prognosis of colorectal cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate colorectal cancer. Additionally, molecular targets (genes and their products) for therapeutic intervention in colorectal and other cancers are described.
Type:
Grant
Filed:
March 15, 1999
Date of Patent:
November 13, 2001
Assignee:
EOS Biotechnology, Inc.
Inventors:
David Mack, Kurt C. Gish, Keith E. Wilson
Abstract: Described herein are methods that can be used for diagnosis and prognosis of colorectal cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate colorectal cancer. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in colorectal and other cancers are described.
Type:
Grant
Filed:
November 9, 1999
Date of Patent:
September 25, 2001
Assignee:
EOS Biotechnology, Inc.
Inventors:
David Mack, Kurt C. Gish, Keith E. Wilson
Abstract: This invention provides an apparatus for preparing chemical libraries. The apparatus includes (1) a carousel comprising a plurality of reaction mounts having at least one reaction well; (2) a rotator that rotates the carousel step-wise; (3) a fluid delivery system; (4) a drain system; and (5) a programmable computer that controls the operation of the apparatus, including the rotator, the fluid delivery system, the drain system and other systems in the apparatus. The preparation of chemical libraries involves rotating the carousel through a plurality of stations. At each station, a physical step in a reaction protocol is carried out on the reaction wells of the mount docked at the station.
Type:
Grant
Filed:
May 18, 1999
Date of Patent:
July 24, 2001
Assignee:
EOS Biotechnology, Inc.
Inventors:
Herbert L. Heyneker, Kim D. Ha, David K. Steinmiller, Victor Simonyi