Patents Assigned to Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S.
  • Process for the preparation of 4-amino-1-hydroxybutylidene-1, 1-biphosphonic acid
    Patent number: 7009071
    Abstract: This invention is related with the preparation of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid with phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglycerides such as plant or animal oils or their derivatives; and recovering of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof are described. The main feature of the invention is in the use of the above defined non-ionic emulgators in the phosphonylation reaction.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: March 7, 2006
    Assignee: Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S.
    Inventors: Kadir Dabak, A. Evren Ozarslan, Filiz Sahbaz, Tuncer Aslan