Abstract: An ablation system (3300) includes a support (3310), a delivery device (3320) configured to deliver the support (3310) to a target tissue, and an ablation element (3330) including a first conductive portion (3331) and a second conductive portion (3332). The first conductive portion (3331) is provided on the support (3310). The second conductive portion (3332) is provided on the support (3310) or the delivery device (3320) or independently from the support (3310) and the delivery device (3320). Both the first conductive portion (3331) and the second conductive portion (3332) are electrically connected to an external pulse ablation source, and the first conductive portion (3331) and the second conductive portion (3332) are configured to transmit pulse ablation energy with different polarities to the target tissue.

Abstract: An electric hydraulic floor jack includes a variable plunger structure provided on a motor base and an oil pump base. The variable plunger structure includes a piston hole formed in the oil pump base and communicating with an oil chamber and an oil inlet passage, a plunger sleeve provided at a port of the piston hole, a plunger slidably provided in the plunger sleeve, a U-shaped piston slidably provided in the piston hole, a valve trim slidably provided on the piston, a spring provided in the piston hole and sleeved on the valve trim, and an eccentric wheel provided on an output shaft of a speed reducer. The plunger is driven by the eccentric wheel in cooperation with the spring to continuously make a linear reciprocating motion, thereby continuously opening and closing the check valve, and pumping oil into the cylinder to push the piston rod for lifting work.

Abstract: An ablation catheter and an ablation system are provided. The ablation catheter includes a sheath and an ablation assembly. The ablation assembly is disposed at a distal end of the sheath for performing ablation and isolation on a target tissue area. The ablation system includes the ablation device and a mapping device, the mapping device includes a mapping electrode arranged at a distal end of the ablation catheter, and the mapping electrode is used for collecting electrophysiological signals in the target tissue area.

Abstract: An ablation device includes an ablation assembly and an adjustment assembly provided at the proximal end of the ablation assembly. The ablation assembly includes a support skeleton and an ablation member provided on the support skeleton. The adjustment assembly includes an inner sheath catheter, an outer sheath catheter and a diameter adjustment module. The outer and inner sheath catheters are movably sleeved in an axial direction, the distal end of the outer sheath catheter is connected to the proximal end of the support skeleton, the distal end of the inner sheath catheter is connected to the distal end of the support skeleton, and the inner sheath catheter is connected to the diameter adjustment module. The diameter adjustment module is movable in the axial direction to drive the inner sheath catheter to move axially relative to the outer sheath catheter, so that the support skeleton deforms to change its radial size.

Abstract: The present application provides an occluder, for use in occluding a defect in a vascular system. The occluder comprises a first occlusion disc, a second occlusion disc, and a tightening wire; the first occlusion disc and the second occlusion disc are used for covering different openings of a defect, respectively; a connector is provided on the first occlusion disc; the connector is provided with a wire passing hole; the tightening wire passes through the wire passing hole of the connector; two ends of the tightening wire pass through the second occlusion disc, and form an adjustment wire knot on the side of the second occlusion disc facing away from the first occlusion disc; the distance between the first occlusion disc and the second occlusion disc can be adjusted by the ends of the tightening wire. The present application also provides an occlusion system having the occluder.

Abstract: An ablation device and an ablation system provided with an ablation device, include an ablation assembly and an adjustment assembly provided at the proximal end of the ablation assembly. The adjustment assembly includes an outer catheter and an inner catheter which extend axially. The ablation assembly includes a supporting framework and an ablation member provided on the supporting framework. The supporting framework includes a positioning frame and a bearing frame. The positioning frame is provided at the distal end relative to the bearing frame, the distal end of the outer catheter is connected to the proximal end of the bearing frame, the distal end of the inner catheter is connected to the distal end of the positioning frame. During moving of the inner catheter relative to the outer catheter, the supporting framework deforms, and the deformation ratio of the positioning frame is less than that of the bearing frame.

Abstract: Disclosed is an occluder for occluding a defect in a vasculature. The occluder includes: two occluding disks and a tightening element. The two occluding disks is configured for covering different openings of the defect; wherein the tightening element includes a tightening thread, the tightening thread passing through the defect and being connected to the two occluding disks, the tightening thread has a length between the two occluding disks and the length is adjustable by means of a free end of the tightening thread. Further provided are an occluding system provided with the occluder, a knotting method for the tightening element of the occluder and a method for occluding an oval foramen with the occluder.

Abstract: A left atrial appendage occluder with advanced connection manner and a manufacturing method thereof are provided. The left atrial appendage occluder includes a sealing portion and an anchoring portion. Each of the sealing portion and the anchoring portion is provided with a connection part formed by converging a corresponding shape of the sealing portion or the anchoring portion respectively. The connection parts of the sealing portion and the anchoring portion extend toward each other to be fixed and misaligned with each other.

Abstract: Exemplary apparatuses and methods of killing or deactivating bacteria are disclosed herein. An exemplary apparatus for killing or deactivating bacteria includes a plasma vapor chamber. The plasma vapor chamber has a vapor inlet for allowing a vapor into the chamber, a high voltage electrode, one or more grounding electrodes. The one or more grounding electrodes at least partially surrounding the plasma vapor chamber. The plasma vapor chamber includes an outlet for allowing fluid to flow out of the chamber. When the chamber is filled with vapor for a period of time sufficient to saturate the chamber with vapor, the high voltage electrode is energized to generate plasma throughout the chamber.

Abstract: Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time. In some embodiments, the fluid includes water. In some embodiments, the spore is Clostridium difficile and in some is Bacillus Anthracis. In some embodiments, the fluid is in the form of a vapor, a fog, a spray, a mist or an aerosol, which may be activated prior to or after applying the fluid to a surface. In some embodiments, peroxynitrite is created in the fluid during the method. Another exemplary embodiment of killing or deactivating a spore includes treating spores with direct plasma or indirect plasma for a period of time and applying an antimicrobial to the spores. In some embodiments, the antimicrobial is an alcohol, a bleach or an alcohol-based sanitizer.

Abstract: Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time. In some embodiments, the fluid includes water. In some embodiments, the spore is Clostridium difficile and in some is Bacillus Anthracis. In some embodiments, the fluid is in the form of a mist and in some is in the form of a vapor. In some embodiments, peroxynitrite is created in the fluid during the method. Another exemplary embodiment of killing or deactivating a spore includes treating spores with direct plasma or an indirect plasma for a period of time and applying an antimicrobial to the spores. In some embodiments, the antimicrobial is an alcohol, a bleach or an alcohol-based sanitizer.

Abstract: Exemplary methods of treating tissue that has been harvested for transplant are disclosed herein. An exemplary method of preparing corneal tissue for transplant includes obtaining corneal tissue that has been harvested for transplanting and exposing the corneal tissue to a plasma-activated fluid for a period of time.

Abstract: Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time. In some embodiments, the fluid includes water. In some embodiments, the spore is Clostridium difficile and in some is Bacillus Anthracis. In some embodiments, the fluid is in the form of a mist and in some is in the form of a vapor. In some embodiments, peroxynitrite is created in the fluid during the method. Another exemplary embodiment of killing or deactivating a spore includes treating spores with direct plasma or an indirect plasma for a period of time and applying an antimicrobial to the spores. In some embodiments, the antimicrobial is an alcohol, a bleach or an alcohol-based sanitizer.

Abstract: Exemplary embodiments of shape conforming dielectric barrier discharge (DBD) plasma generators are disclosed herein. One exemplary embodiment includes a flexible pad and a plurality of electrodes located in the pad within close proximity of each other, and a flexible dielectric barrier surrounding the plurality of electrodes and separating the plurality of electrodes from each other. Wherein when a high voltage pulse is applied to one or more of the plurality of electrodes, plasma is produced between a surface of the flexible pad and a portion of the body in close proximity to the flexible pad.

Abstract: Exemplary systems and methods of delivering DNA vaccines are disclosed herein. An exemplary methodology of delivering DNA vaccines includes providing a plasma generator for applying plasma to a treatment area for a sufficient period of time to open one or more pores. Applying a topical DNA vaccine to the treatment area and waiting for a period of time to allow the DNA vaccine to travel through the one or more pores. The exemplary methodology further includes applying plasma to the treatment area at a setting sufficient to cause intracellular uptake of the DNA vaccine.

Abstract: A plate heat exchanger (10) of the double plate type having a plurality of stacked plate elements, each comprising a first plate (1) and a second plate (9). At least the first plate (1) is provided with a surface pattern with a plurality of dimples (5) defining a first distance to a plate plane (8), and a plurality of canal parts (6) defining a second, smaller, distance to the plate plane (8). The first plate (1) and the second plate (9) are joined in such a manner that the protruding areas (5, 6) in combination form flow paths (11) being fluidly connected to rim portions (3) of the plates (1, 9). The heat exchanger (10) provides efficient leakage detection via the flow paths (11) while ensuring a good thermal contact between heat exchanging fluids through the plates (1, 9) via flat portions (7) between the protruding parts (5, 6).

Abstract: Exemplary methods of opening pores and moving molecules into tissue comprising, applying plasma to the surface of tissue and applying a carrier including one or more molecules to the surface of the tissue are disclosed herein.

Abstract: A sanitization station including a fluid source and one or more plasma generators for generating non-thermal plasma is disclosed. One or more nozzles spray a mist or stream of fluid through plasma generated by the one or more plasma generators to activate the fluid. The fluid is then used to sterilize an object. Another sanitization station includes a chamber for holding a fluid and a plasma generator in fluid communication with the chamber for generating plasma. A circulating source moves the fluid in the chamber past plasma generated by the plasma generator to activate the fluid and one or more spray nozzles coat the surface of an object with fluid that is activated by plasma.

Abstract: Exemplary methods for killing or deactivating bacteria are provided herein. One exemplary method includes providing a plasma system and a filter below the plasma system. Energizing the plasma generator to create indirect plasma downstream of the filter and activating a fluid with the indirect plasma and applying the activated fluid to bacteria is shown to deactivate and kill bacteria.

Abstract: Exemplary embodiments of solutions of plasma activated water and peroxyacetic acid are disclosed herein. In addition, exemplary embodiments of methods for making solutions are disclosed herein. Some methods include exposing water to a plasma gas to activate the water, adding acetic acid to the activated water; and mixing the acetic acid and activated water to form a solution. Additional exemplary methods include adding acetic acid to water to form a solution, mixing solution of acetic acid and water together; and exposing the solution to a plasma gas to activate the solution. Another exemplary embodiment includes exposing water to a plasma gas to activate the water; adding an acetyl group donor to the activated water; and mixing the acetyl group donor and activated water to form a solution.