Abstract: The present application relates to compositions for treatment of eye disorders, particularly for treatment of dry eye disease (DED) and meibomianitis, wherein the composition comprises very long chain polyunsaturated fatty acids. Further, the invention provides a method for treatment of DED and meibomianitis of a subject, comprising administering to the subject a composition comprising very long chain polyunsaturated fatty acids derived from natural oils. The compositions for use are suitable for oral and local applications.

Abstract: The present application relates to compositions for treatment of eye disorders, particularly for treatment of dry eye disease (DED) and meibomianitis, wherein the composition comprises very long chain polyunsaturated fatty acids. Further, the invention provides a method for treatment of DED and meibomianitis of a subject, comprising administering to the subject a composition comprising very long chain polyunsaturated fatty acids derived from natural oils. The compositions for use are suitable for oral and local applications.

Abstract: A method of producing a composition comprising a high concentration of very long chain polyunsaturated fatty acids (VLCPUFAs) from natural oils such as fish oil, squid oil, algal oil and krill oil. In addition, a composition comprising a high concentration of very long chain polyunsaturated fatty acids isolated from such natural sources; as well as to a process for isolating separate fractions of very long chain polyunsaturated fatty acids having identical chain lengths but different degrees of unsaturation from such highly concentrated compositions is disclosed.

Abstract: An enzymatic process for the kinetic separation of alkyl esters under organic solvent free conditions is disclosed. Alkyl esters obtained from e.g. fish oil are reacted with glycerol, in the presence of water, at different rates in an evacuated chamber. The reaction is terminated prior to reaching equilibrium and the enriched alkyl ester fraction is isolated from the reaction mixture by short path distillation.

Abstract: A method of producing a composition comprising a high concentration of very long chain polyunsaturated fatty acids (VLCPUFAs) from natural oils such as fish oil, squid oil, algal oil and krill oil. In addition, a composition comprising a high concentration of very long chain polyunsaturated fatty acids isolated from such natural sources; as well as to a process for isolating separate fractions of very long chain polyunsaturated fatty acids having identical chain lengths but different degrees of unsaturation from such highly concentrated compositions is disclosed.

Abstract: The present invention relates to compositions suitable for improving oxidative stability of marine oils, marine oils having improved oxidative stability as well as methods for manufacturing such compositions.

Abstract: In one aspect, the present invention is directed to a method for obtaining an enriched composition of long chain monounsaturated fatty acids from an oil composition, typically a fish oil composition, comprising both long chain monounsaturated fatty acids and long chain polyunsaturated fatty acids. In another aspect, the present invention is directed to a composition comprising at least 70% by weight of long chain monounsaturated fatty acids.