Abstract: The invention provides methods, kits and reagents for diagnosing fibromyalgia (FM) in an individual by determining whether the levels of one or more cytokines in the individual are altered, as compared to control levels. The altered level(s) or patterns of expression of the cytokines measured in the affected individual compared to the level from the control is predictive/indicative of FM in the individual.
Abstract: The invention provides methods and compositions for treating fibromyalgia (FM) and chronic fatigue syndrome (CFS) in an individual. The methods provided herein entail administering a composition comprising an isolated Mycobacterium or antigenic fragments derived therefrom. Also provided herein are methods for assessing alleviation of symptoms and/or alteration of immune system functioning following administration of a composition comprising an isolated Mycobacterium or antigenic fragments derived therefrom.
Abstract: The invention provides methods, kits and reagents for diagnosing fibromyalgia (FM) in an individual by determining whether the levels of one or more cytokines in the individual are altered, as compared to control levels. The altered level(s) or patterns of expression of the cytokines measured in the affected individual compared to the level from the control is predictive/indicative of FM in the individual.
Abstract: Cellular immunologic methods are disclosed for determining human health effects of exposures to environmental molds and toxins. In one embodiment, a method for assessing a patient's exposure to a mold strain is provided. The method comprises measuring cytokine production in at least the peripheral blood mononuclear cells of a mammal suspected of being exposed to mold or other toxin and determining if there is a decreased production of cytokines in the mammal suspected of being exposed to mold or other toxin when compared to the production of cytokines produced in a mammal not suspected of being exposed to mold or other toxin. Other methods, including methods of diagnosing respiratory disorders, including asthma, are also disclosed.
Type:
Application
Filed:
August 5, 2011
Publication date:
February 7, 2013
Applicant:
EPICGENETICS, INC.
Inventors:
Bruce S. Gillis, Igor Mikhailovich Gavin