Patents Assigned to Epicore Biosystems, Inc.
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Patent number: 11559225Abstract: A wearable biofluid volume and composition system includes a microfluidic flexible fluid capture substrate having a microfluidic channel configured as a sweat collection channel and is configured to be worn on a human body and to collect and analyze biofluid. The microfluidic flexible fluid capture substrate further has a plurality of conductive traces and electrodes. An electronic module is attached to the microfluidic flexible fluid capture substrate and is configured to measure and analyze data from the biofluid collected by the microfluidic flexible fluid capture substrate and to transmit the analyzed data to a smart device.Type: GrantFiled: May 17, 2022Date of Patent: January 24, 2023Assignee: Epicore Biosystems, Inc.Inventors: Stephen P. Lee, Adam Leech, Weihua Li, Alan P. Scarth, Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Melissa Seib, Jessica Wallace
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Publication number: 20220313226Abstract: A sweat collection system includes a sweat collection device configured to be adhered to the skin of a user to collect sweat for storage, extraction, and analysis. The sweat collection device includes a flexible body having a first, outwardly facing surface and a second, skin-facing surface, and a sweat collection channel formed in the body and having a first end defining a sweat inlet port, and a second end defining a sweat outlet port. A biochemical assay well is formed in the sweat channel, and a dye is disposed therein and is positioned to react with sweat in the sweat channel and to provide an indicator of the flow of the sweat in the sweat channel. The sweat collection device is affixed to the skin to determine a total volume of sweat collected over a known period, and a graph of sweat volume over time is plotted to determine a sweat rate.Type: ApplicationFiled: April 15, 2022Publication date: October 6, 2022Applicant: Epicore Biosystems, Inc.Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj
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Patent number: 11412959Abstract: The present invention provides a biofluid sensing device capable of concentrating a biofluid sample with respect to a target analyte, so that the analyte can be accurately detected or measured by EAB sensors. Methods for using such a device provide qualitative information about the presence of the analyte, and/or quantitative information about relative concentrations of the analyte in the biofluid. The disclosed device includes a concentration channel for concentrating the biofluid sample, as well as a selectively permeable membrane, one or more EAB sensors, and one or more secondary sensors carried on a water-impermeable substrate. A method for using the disclosed device to collect a biofluid sample, concentrate the sample relative to a target analyte, and measure the target analyte is also disclosed.Type: GrantFiled: February 7, 2018Date of Patent: August 16, 2022Assignee: Epicore Biosystems, Inc.Inventors: Robert Beech, Gavi Begtrup, Jason Heikenfeld, Jacob A. Bertrand
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Patent number: 11406321Abstract: A sweat sensing device includes a flexible body having a first, outwardly facing surface and a second, skin facing surface and a sweat channel formed in the body, the sweat channel having a first end defining a fluid inlet and a second end. A biochemical assay well formed in the sweat channel and an assay material is disposed in the biochemical assay well, the assay material positioned to react with sweat traveling through the sweat channel and to provide one of a visual indicator and an indicator detectable by a camera and connected processor of the flow of the sweat in the sweat channel.Type: GrantFiled: July 24, 2018Date of Patent: August 9, 2022Assignee: Epicore Biosystems, Inc.Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj
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Patent number: 11337681Abstract: A sweat collection device includes a flexible body having a first, outwardly facing surface and a second, skin-facing surface, and a sweat collection channel formed in the body, the sweat collection channel having a first end defining a sweat inlet port, and a second end defining a sweat outlet port. The sweat inlet port and the sweat outlet port are configured to be closed and sealed such that the sweat collection device and the collected sweat therein may be stored and shipped.Type: GrantFiled: November 21, 2018Date of Patent: May 24, 2022Assignee: Epicore Biosystems, Inc.Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj
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Publication number: 20210186470Abstract: A sweat collection device includes a flexible body having a first, outwardly facing surface and a second, skin-facing surface, and a sweat collection channel formed in the body, the sweat collection channel having a first end defining a sweat inlet port, and a second end defining a sweat outlet port. The sweat inlet port and the sweat outlet port are configured to be closed and sealed such that the sweat collection device and the collected sweat therein may be stored and shipped.Type: ApplicationFiled: November 21, 2018Publication date: June 24, 2021Applicant: Epicore Biosystems, Inc.Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj
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Publication number: 20200397315Abstract: A system for collecting and analyzing sweat includes a sweat sensing device having at least one sensor configured to sense one of physiologic information, biologic information, biochemical information, and biometric information, from skin of a person to whom the sweat sensing device is attached. A wireless transmitter is mounted to the sweat sensing device and electrically connected to the at least one sensor. An interactive console is configured to produce a real time feedback to an operator of the system for collecting and analyzing sweat, includes a wireless receiver, and is in wireless communication with the sweat sensing device. The interactive console is further configured to receive data from the at least one sensor, display the data received from the at least one sensor, adjust an environmental condition based on the sensor data received, and display the adjustment to the environmental condition.Type: ApplicationFiled: June 19, 2020Publication date: December 24, 2020Applicant: Epicore Biosystems, Inc.Inventors: Milan S. Raj, Stephen P. Lee, Alexander J. Aranyosi, Jeffrey B. Model, Roozbeh Ghaffari
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Publication number: 20200129112Abstract: A sweat sensing device includes a flexible body having a first, outwardly facing surface and a second, skin facing surface and a sweat channel formed in the body, the sweat channel having a first end defining a fluid inlet and a second end. A biochemical assay well formed in the sweat channel and an assay material is disposed in the biochemical assay well, the assay material positioned to react with sweat traveling through the sweat channel and to provide one of a visual indicator and an indicator detectable by a camera and connected processor of the flow of the sweat in the sweat channel.Type: ApplicationFiled: July 24, 2018Publication date: April 30, 2020Applicant: Epicore Biosystems, Inc.Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj