Patents Assigned to EPIRIUM BIO INC.
  • Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
    Patent number: 11542298
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: January 3, 2023
    Assignee: Epirium Bio Inc.
    Inventors: Sundeep Dugar, Dinesh Mahajan, George Frederic Schreiner
  • Compounds and compositions for the treatment of muscular disorders and bone disorders
    Patent number: 11273144
    Abstract: The present invention relates to compounds and compositions and their applications as pharmaceuticals for treating, preventing, or reversing injury to skeletal or cardiac muscles, for treating or preventing diseases relating to the structure and function of skeletal or cardiac muscle, and for inducing regeneration or restructuring of skeletal or cardiac muscle as a means of treating diseases relating to abnormalities in skeletal or cardiac muscle structure and function in a human or animal subject. Further aspects relate to the same or similar applications for bone and bone diseases.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: March 15, 2022
    Assignee: EPIRIUM BIO INC.
    Inventors: George Frederic Schreiner, Guillermo Ceballos, Sundeep Dugar
  • Methods and compositions for treatment of mitochondrial toxicity
    Patent number: 11154546
    Abstract: The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In various aspects, the present invention comprises administering one or more compounds selected from the group consisting of epicatechin, an epicatechin derivative, catechin, a catechin derivative, nicorandil, and a nicorandil derivative in an amount effective to ameliorate mitochondrial toxicity caused by administration of a chemical, food, or drug.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: October 26, 2021
    Assignee: Epirium Bio Inc.
    Inventors: Francisco Villarreal, Alan Maisel, George Schreiner, Guillermo M. Ceballos Reyes, Pam Taub
  • Utility of (+) epicatechin and their analogs
    Patent number: 10898465
    Abstract: The present invention pertains to the enhanced activity of (+) epicatechin over (?) epicatechin. The present invention is related to novel analogs of (+) epicatechin of the formula (I), which enhances the pharmacokinetics and therefore the pharmacodynamics of (+) epicatechin. The present invention is related to analogs of (+) epicatechin of the formula (I). The general structure of the analogs of the present invention may be represented by Formula (I): Formula (I) wherein A and B are independently OR1 and C and D are independently OH; wherein R1 is independently C1 to C10 lower straight or branched chain acyclic or cyclic alkyl, or is selected from the group comprising, hydroxy butyric acid, dichloroacetic acid; phenyl butyric acid; valproic acid.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: January 26, 2021
    Assignee: Epirium Bio Inc.
    Inventors: Sundeep Dugar, George Schreiner, Somdutta Sen
  • Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
    Patent number: 10618933
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: April 14, 2020
    Assignee: EPIRIUM BIO INC.
    Inventors: Sundeep Dugar, Dinesh Mahajan, George Frederic Schreiner