Abstract: The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (1)-(X) or Compounds (1)-(92) of Table 1) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotropic lateral sclerosis, glaucoma, ischaemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome.
Type:
Application
Filed:
February 26, 2015
Publication date:
April 20, 2017
Applicants:
Epirus Biopharmaceuticals, Inc., Epirus Biopharmaceuticals, Inc.
Inventors:
Hassan PAJOUHESH, Richard HOLLAND, Lingyun ZHANG, Hossein PAJOUHESH, Jason LAMONTAGNE, Brendan WHELAN