Abstract: Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.
Type:
Grant
Filed:
June 8, 2010
Date of Patent:
December 9, 2014
Assignee:
Epitarget AS
Inventors:
Cecilia Leal Lauten, Karen Sibylla Røgnvaldsson, Sigrid Fossheim, Esben A. Nilssen, Tove J. Evjen
Abstract: Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.
Type:
Grant
Filed:
December 9, 2008
Date of Patent:
July 1, 2014
Assignee:
Epitarget AS
Inventors:
Cecilia Leal Lauten, Karen Sibylla Rognvaldsson, Sigrid L. Fossheim, Esben A. Nilssen, Tove J. Evjen
Abstract: Novel acoustically sensitive drug carrying particles comprising low concentrations of phosphatidylethanolamine are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.
Type:
Application
Filed:
December 21, 2010
Publication date:
November 15, 2012
Applicant:
EPITARGET AS
Inventors:
Tove Julie Evjen, Esben A. Nilssen, Sigrid L. Fossheim
Abstract: Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.
Type:
Application
Filed:
June 8, 2010
Publication date:
July 26, 2012
Applicant:
EPITARGET AS
Inventors:
Cecilia Leal Lauten, Karen Sibylla Røgnvaldsson, Sigrid L. Fossheim, Esben A. Nilssen, Tove J. Evjen
Abstract: Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their pay-load upon exposure to acoustic energy.
Type:
Application
Filed:
June 8, 2010
Publication date:
June 14, 2012
Applicant:
EPITARGET AS
Inventors:
Esben A. Nilssen, Sigrid L. Fossheim, Tove Julie Evjen
Abstract: Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their pay-load upon exposure to acoustic energy.
Type:
Application
Filed:
June 8, 2010
Publication date:
May 17, 2012
Applicant:
EPITARGET AS
Inventors:
Cecilia Leal Lauten, Karen Sibylla Røgnvaldsson, Sigrid L. Fossheim, Esben A. Nilssen, Tove J. Evjen
Abstract: Novel use of ultrasound sensitive drug carrying particles comprising an alcohol is disclosed, as well as products and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon ultrasound exposure.
Type:
Application
Filed:
December 9, 2008
Publication date:
January 27, 2011
Applicant:
Epitarget AS
Inventors:
Cecilia Leal Lauten, Karen Sibylia Rognvaldsson, Sigrid L. Fossheim, Esben A. Nilssen
Abstract: The current invention discloses a drug delivery system allowing monitoring of spatial position and drug release, as well as methods and uses thereof. More particularly, the drug delivery system comprises drug carrying particles comprising novel combinations of magnetic resonance imaging contrast agents.
Abstract: Disclosed are ultrasound sensitive drug carrying particles, uses and methods thereof, wherein the drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon ultrasound exposure.
Type:
Application
Filed:
September 29, 2008
Publication date:
April 16, 2009
Applicant:
EPITARGET AS
Inventors:
Sigrid Fossheim, Cecilia Leal Lauten, Petras Juzenas, Karen Sibylla Rognvaldsson, Esben A. Nilssen