Abstract: The present invention is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.
Abstract: The present technology is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Grant
Filed:
September 17, 2015
Date of Patent:
February 26, 2019
Assignee:
EPIVAX, INC.
Inventors:
Anne De Groot, William Martin, Daniel S. Rivera
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
October 16, 2018
Publication date:
January 31, 2019
Applicant:
EpiVax, Inc.
Inventors:
Anne De Groot, William Martin, Daniel S. Rivera
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
October 16, 2018
Publication date:
January 31, 2019
Applicant:
EpiVax, Inc.
Inventors:
Anne De Groot, William Martin, Daniel S. Rivera
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne DE GROOT, William MARTIN, Daniel S. RIVERA
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne DE GROOT, William MARTIN, Daniel S. RIVERA
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne De Groot, William Martin, Daniel S. Rivera
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne DE GROOT, William MARTIN, Daniel S. RIVERA
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne DE GROOT, William MARTIN, Daniel S. RIVERA
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne DE GROOT, William MARTIN, Daniel S. RIVERA
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Application
Filed:
June 22, 2018
Publication date:
October 11, 2018
Applicant:
EpiVax, Inc.
Inventors:
Anne DE GROOT, William MARTIN, Daniel S. RIVERA
Abstract: The present invention is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.
Type:
Application
Filed:
April 15, 2016
Publication date:
June 28, 2018
Applicants:
EpiVax, Inc., National Institute of Infectious Diseases
Inventors:
Anne S De Groot, William D Martin, Yoshimasa Takahashi, Manabu Ato
Abstract: The present invention is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.
Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
Type:
Grant
Filed:
January 29, 2008
Date of Patent:
February 8, 2011
Assignee:
Epivax, Inc.
Inventors:
Anne De Groot, William Martin, Daniel S. Rivera