Abstract: A system, apparatus, and method for closed fluid delivery include a bottle holding a quantity of fluid. A membrane is positioned over an opening of the bottle to seal the fluid therein. A closed fluid delivery adapter has a first portion with a first mateable end connectable to the bottle along the opening of the bottle and a second portion having a second mateable end positioned to connect to a container. A fluid pathway is between the first and second portions. A puncturing structure is positioned along the fluid pathway. A removable collar is positioned between the first and second portions. The removable collar prevents the first and second portions from moving closer together. Upon removal of the removable collar, the first and second portions are movable closer together, whereby the puncturing structure punctures the membrane to allow flow of the fluid.