Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Type:
Grant
Filed:
December 20, 2021
Date of Patent:
February 27, 2024
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Sebastian Fruhauf, Michaela Thamhesl, Martin Pfeffer, Dieter Moll, Gerd Schatzmayr, Eva Maria Binder
Abstract: A dispensing apparatus (1) for delivering droplets of fluids such as liquids having a low viscosity or being soft gels onto poultry hatchlings that are present in movably mounted hatchling trays (19) comprising at least one reservoir (18), at least one pumping unit (9), connected to at least one reservoir (18), with at least one manifold (8) connected to at least one pumping unit (9), as well as a control unit. The apparatus comprises a plurality of optionally adjustable fluid atomizers (6) being connected by flexible connecting means (7) to at least one manifold (8), whereby the fluid atomizers (6) are detachably and/or slidably connected on at least one mounting rail (5), and that optionally different types of fluid atomizers (6) are distributed onto the mounting rail (5). Additionally, a method for delivering fluid droplets onto poultry hatchlings present in moving hatchling trays (19) is described.
Type:
Grant
Filed:
July 17, 2018
Date of Patent:
September 12, 2023
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Daniel Petri, Luca Stefano Vandi, Eva Maria Binder, Martin Pfeffer, Stephen Charles John Cole, Dante Lorini
Abstract: The present invention relates to a use of a microorganism of the class Coriobacteriia for promoting gut health of a healthy subject. Also provided is a method for the production of chenodeoxycholic acid (CDCA) and a method for the production of lithocholic acid (LCA).
Type:
Grant
Filed:
December 19, 2018
Date of Patent:
July 4, 2023
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Dian Schatzmayr, Eva Maria Binder, Veronika Nagl, Gerd Schatzmayr
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Type:
Application
Filed:
June 1, 2022
Publication date:
October 13, 2022
Applicant:
Erber Aktiengesellschaft
Inventors:
Sebastian FRUHAUF, Michaela THAMHESL, Martin PFEFFER, Dieter MOLL, Gerd SCHATZMAYR, Eva Maria BINDER
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Type:
Application
Filed:
June 1, 2022
Publication date:
September 15, 2022
Applicant:
Erber Aktiengesellschaft
Inventors:
Sebastian FRUHAUF, Michaela Thamhesl, Martin Pfeffer, Dleter Moll, Gerd Schatzmayr, Eva Maria Binder
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Type:
Application
Filed:
December 20, 2021
Publication date:
June 30, 2022
Applicant:
Erber Aktiengesellschaft
Inventors:
Sebastian FRUHAUF, Michaela THAMHESL, Martin PFEFFER, Dieter MOLL, Gerd SCHATZMAYR, Eva Maria BINDER
Abstract: The use of at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.
Type:
Application
Filed:
July 15, 2021
Publication date:
November 4, 2021
Applicant:
Erber Aktiengesellschaft
Inventors:
Elisabeth MAYER, Barbara NOVAK, Christina SCHWAB-ANDICS, Ursula HOFSTATTER-SCHAEHS, Gerd SCHATZMAYR
Abstract: The invention relates to a polypeptide for the enzymatic detoxification of zearalenone, said polypeptide being a monooxygenase which converts the keto group in position 7 of zearalenone into an ester group, the monooxygenase in particular being an amino acid sequence selected from the group comprising sequence ID No. 1, 2 and 3 or a functional variant thereof. The functional variant and at least one of the amino acid sequences has a sequence identity of at least 60%, preferably at least 70%, more preferably at least 80% and most preferably 90%.
Type:
Grant
Filed:
March 25, 2020
Date of Patent:
October 5, 2021
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Juan Antonio Torres Acosta, Gerhard Adam, Elisavet Kunz-Vekiru, Wulf-Dieter Moll, Rudolf Mitterbauer, Clemens Schmeitzl
Abstract: A method of using at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.
Type:
Grant
Filed:
December 14, 2017
Date of Patent:
August 24, 2021
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Elisabeth Mayer, Barbara Novak, Christina Schwab-Andics, Ursula Hofstätter-Schaehs, Gerd Schatzmayr
Abstract: An alcohol dehydrogenase of sequence ID numbers 2, 3 or 4 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.
Type:
Grant
Filed:
September 20, 2019
Date of Patent:
May 11, 2021
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Eva-Maria Binder, Barbara Weber, Claudia Bernard
Abstract: In a method for extracting contaminants from agrarian products or foods or animal feeds containing agrarian products, comprising contacting a solvent for the contaminants with the agrarian products containing or having adsorbed the contaminants, or the foods or animal feeds, and at least one extraction buffer in an optionally closable mixing vessel, the extraction buffer, which is contained in a film soluble in the solvent and is supplemented with at least one surfactant, in particular nonionic surfactant, and the contaminated agrarian product or food or animal feed are contacted with cold water as solvent in the mixing vessel, and the extraction buffer and the contaminants are brought into solution by agitating or stirring in the mixing vessel; and apparatus therefor.
Type:
Grant
Filed:
June 3, 2015
Date of Patent:
March 30, 2021
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Eva-Maria Binder, Barbara Cvak, Alois Schiessl, Georg Häubl
Abstract: The invention is directed to a particle containing at least a volatile substance comprising a core comprising at least one matrix material and the at least one volatile substance and at least one coating layer, whereby a first coating layer is a non-confluent layer comprising at least a carrier material, whereby optionally the non-confluent layer contains at least one hydrophobic substance, and optionally the particle is surrounded by at least one confluent layer and/or further non-confluent layer(s) as well as to a process for producing the same.
Type:
Grant
Filed:
September 19, 2017
Date of Patent:
March 2, 2021
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Pia Gottschalk, Eva-Maria Binder, Franz Waxenecker, Carina Schieder, Anne-Christine Hunger, Stephen Charles John Cole
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Type:
Application
Filed:
July 21, 2020
Publication date:
December 3, 2020
Applicant:
Erber Aktiengesellschaft
Inventors:
Sebastian Fruhauf, Michaela Thamhesl, Martin Pfeffer, Dieter Moll, Gerd Schatzmayr, Eva Maria Binder
Abstract: The invention relates to a polypeptide for the enzymatic detoxification of zearalenone, said polypeptide being a monooxygenase which converts the keto group in position 7 of zearalenone into an ester group, the monooxygenase in particular being an amino acid sequence selected from the group comprising sequence ID No. 1, 2 and 3 or a functional variant thereof. The functional variant and at least one of the amino acid sequences has a sequence identity of at least 60%, preferably at least 70%, more preferably at least 80% and most preferably 90%.
Type:
Application
Filed:
March 25, 2020
Publication date:
October 22, 2020
Applicant:
Erber Aktiengesellschaft
Inventors:
Juan Antonio TORRES ACOSTA, Gerhard ADAM, Elisavet KUNZ-VEKIRU, Wulf-Dieter MOLL, Rudolf MITTERBAUER, Clemens SCHMEITZL
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Type:
Grant
Filed:
October 16, 2018
Date of Patent:
September 22, 2020
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Sebastian Fruhauf, Michaela Thamhesl, Martin Pfeffer, Dieter Moll, Gerd Schatzmayr, Eva Maria Binder
Abstract: The invention relates to a preparation comprising at least one chemical fungicide. In addition to the at least one chemical fungicide, a mixture is included which comprises at least the strains of Aureobasidium pullulans DMS 14940 and DSM 14941. The at least one chemical fungicide and the mixture of the strains Aureobasidium pullulans are present in the preparation in synergistically active quantities, and the at least one chemical fungicide is selected from fludioxinil or a combination containing fludioxinil and at least one second chemical fungicide. The invention also relates to the use of the preparation and to a method for the prophylaxis or the reduction of the spread of at least one plant disease caused by a fungal pathogen.
Type:
Application
Filed:
March 7, 2018
Publication date:
September 3, 2020
Applicant:
Erber Aktiengesellschaft
Inventors:
Eva-Maria BINDER, Christina Maria DONAT
Abstract: The use of at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.
Type:
Application
Filed:
December 14, 2017
Publication date:
August 27, 2020
Applicant:
Erber Aktiengesellschaft
Inventors:
Elisabeth MAYER, Barbara NOVAK, Christina SCHWAB-ANDICS, Ursula HOFSTÄTTER-SCHAEHS, Gerd SCHATZMAYR
Abstract: A dispensing apparatus (1) for delivering droplets of fluids such as liquids having a low viscosity or being soft gels onto poultry hatchlings that are present in movably mounted hatchling trays (19) comprising at least one reservoir (18), at least one pumping unit (9), connected to at least one reservoir (18), with at least one manifold (8) connected to at least one pumping unit (9), as well as a control unit. The apparatus comprises a plurality of optionally adjustable fluid atomizers (6) being connected by flexible connecting means (7) to at least one manifold (8), whereby the fluid atomizers (6) are detachably and/or slidably connected on at least one mounting rail (5), and that optionally different types of fluid atomizers (6) are distributed onto the mounting rail (5). Additionally, a method for delivering fluid droplets onto poultry hatchlings present in moving hatchling trays (19) is described.
Type:
Application
Filed:
July 17, 2018
Publication date:
June 4, 2020
Applicant:
Erber Aktiengesellschaft
Inventors:
Daniel PETRI, Luca Stefano VANDI, Eva Maria BINDER, Martin PFEFFER, Stephen Charles John COLE, Dante LORINI
Abstract: An additive for selenium-containing forage, primarily comprising plants or plant parts, such as cereal, corn, grass, or alfalfa, including at least one salt detoxifying inorganic trichothecene and/or zearalenone, with an alkali or earth alkali metal sulfite and perhaps a selenium containing salt being included as the inorganic salt detoxifying trichothecene and/or zearalenone.
Type:
Grant
Filed:
December 10, 2012
Date of Patent:
March 3, 2020
Assignee:
ERBER AKTIENGESELLSCHAFT
Inventors:
Eva-Maria Binder, Dian Alexandra Schatzmayr, Heidi Elisabeth Schwartz
Abstract: An alcohol dehydrogenase of sequence ID numbers 2, 3 or 4 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.
Type:
Application
Filed:
September 20, 2019
Publication date:
January 9, 2020
Applicant:
Erber Aktiengesellschaft
Inventors:
Eva-Maria BINDER, Barbara Weber, Claudia Bernard