Abstract: An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3% (p/p)and a pH buffer solution; a process to prepare said solid composition. Also a reconstituted solution of melphalan comprising a solid composition of melphalan lyophilized reconstituted wherein said solution is aqueous, a perfusion free of organic solvent and a kit.
Type:
Application
Filed:
July 4, 2011
Publication date:
May 23, 2013
Applicant:
ERIOCHEM
Inventors:
José Castillo, José Bernardo Iturraspe, José Lucio Nuñez