Patents Assigned to ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALD
  • Screening methods for transfusion related acute lung injury (TRALI)
    Patent number: 9963741
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: May 8, 2018
    Assignees: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD, DRK BLUTSPENDEDIENST WEST GMBH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Imidazolium salts and carbene metal complexes based thereon for use as bioanalytical markers for biomolecules
    Patent number: 9150515
    Abstract: The present invention relates to imidazolium salts, particularly imidazolium salts of the general formula I as well as the respective carbene metal complexes and their utilization as bioanalytical tags for biomolecules.
    Type: Grant
    Filed: September 5, 2011
    Date of Patent: October 6, 2015
    Assignee: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD
    Inventor: Olaf Kuehl
  • Screening methods for transfusion related acute lung injury (TRALI)
    Patent number: 8999651
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: April 7, 2015
    Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Screening Methods for Transfusion Related Acute Lung Injury (TRALI)
    Publication number: 20130189696
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence.
    Type: Application
    Filed: March 18, 2013
    Publication date: July 25, 2013
    Applicants: DRK BLUTSPENDEDIENST WEST GMBH, ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALD
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Novel Imidazolium Salts and Carbene Metal Complexes Based Thereon for Use as Bioanalytical Markers for Biomolecules
    Publication number: 20130171071
    Abstract: The present invention relates to imidazolium salts, particularly imidazolium salts of the general formula I as well as the respective carbene metal complexes and their utilisation as bioanalytical tags for biomolecules.
    Type: Application
    Filed: September 5, 2011
    Publication date: July 4, 2013
    Applicant: ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALD
    Inventor: Olaf Kuehl
  • Screening methods for transfusion related acute lung injury
    Patent number: 8435733
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: May 7, 2013
    Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Screening Methods for Transfusion Related Acute Lung Injury
    Publication number: 20120070834
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Application
    Filed: November 29, 2011
    Publication date: March 22, 2012
    Applicants: DRK BLUTSPENDIENST WEST GMBH, ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD
    Inventors: ANDREAS GREINACHER, JAN WESCHE, JUERGEN BUX, ANGELIKA REIL
  • Screening methods for transfusion related acute lung injury (TRALI)
    Patent number: 8084216
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: December 27, 2011
    Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Screening Methods for Transfusion Related Acute Lung Injury (TRALI)
    Publication number: 20100055706
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 4, 2010
    Applicants: ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALD, DRK BLUTSPENDEDIENST WEST GMBH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Use Of Mrp4-Inhibitors For The Treatment And/Or Prophylaxis Of Cardiovascular Diseases
    Publication number: 20070212366
    Abstract: The invention relates to the use of inhibitors of the multidrug resistance protein 4 (MRP4) in thrombocytes for the treatment and/or prophylaxis of cardiovascular diseases.
    Type: Application
    Filed: November 5, 2004
    Publication date: September 13, 2007
    Applicant: ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALD
    Inventors: Andreas Greinacher, Heyo Kroemer, Gabriele Jedlitschky
  • Use of multifunctional transcription factor yin-yang-1 and variants thereof for treating illnesses, especially type 1 diabetes
    Publication number: 20070141072
    Abstract: The present invention relates to the influence of the activity and/or the expression of the multifunctional transcription factor Yin Yang 1 (YY1), and of variants thereof, for the treatment of many different illnesses. The invention especially relates to a mutated nucleic acid sequence which encodes a variant of the human YY1 and has a protective action against diabetes, according to the present invention.
    Type: Application
    Filed: December 19, 2003
    Publication date: June 21, 2007
    Applicant: ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALD
    Inventors: Ingrid Kloting, Nora Kloting