Abstract: A system and method for two way short message service (SMS)-enabled BGM and related communications is presented. The method includes receiving, by a processing device integrated with a blood glucose meter (BGM), a first short message service (SMS) message comprising a question, presenting the question at the BGM, receiving a response to the question, translating the response to the question into a second SMS message, translating blood glucose measurement information into a third SMS message, the blood glucose measurement information received from a test of a user by the BGM, and transmitting the second and third SMS messages to a receiver.