Abstract: Methods for treating or preventing kidney diseases and fibrosis, such as chronic kidney disease (CKD), kidney fibrosis, heart fibrosis, uterine fibrosis, and cystic fibrosis, with compounds of Formulae (I), (IA), (IB), (IC), (ID), (IE), (IF), (IG), (IH), (IJ), (II), (III), (IIIA), and (IIIB); pharmaceutically acceptable salts and solvates thereof; and compositions thereof.
Type:
Grant
Filed:
January 24, 2022
Date of Patent:
August 29, 2023
Assignee:
Espervita Therapeutics, Inc.
Inventors:
Daniela Carmen Oniciu, Gregory R. Steinberg, Spencer Heaton, Roger Schofield Newton, James Stuart Vincent Lally, Jaya Gautam