Abstract: Provided are immediate or prolonged administration of certain potassium ATP (KATP) channel openers, optionally in combination with growth hormone, to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of KATP channel openers that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are methods of co-administering KATP channel openers with other drugs (e.g., in combination with growth hormone) to treat diseases of humans and animals (e.g., Prader-Willi Syndrome (PWS), Smith-Magenis syndrome (SMS), and the like.

Abstract: A ratchet buckle and belt system are disclosed. The ratchet belt includes a ratcheting mechanism configured to releasably engage with a notch strip of the belt. The ratcheting mechanism has a first pawl and a second pawl each rotatably coupled to a ratchet pin. The first pawl includes a first ratcheting tab and a first release lever wherein the first release lever is configured to rotate the first pawl and disengage the first ratcheting tab from the notch strip. The second pawl includes a second ratcheting tab and a second release lever wherein the second release lever is configured to rotate the second pawl and disengage the second ratcheting tab from the notch strip. When both the first and second ratcheting tabs are simultaneously disengaged from the notch strip, the ratcheting mechanism is disengaged from the belt forming a disengaged configuration.

Abstract: A wristwatch is provided incorporating one of a plurality of possible case embodiments, such as, without limitation, mechanical and electronic movements, and a novel ratcheting buckle and corresponding strap, whereby the user may incrementally adjust fitment of the watch via a ratcheting mechanism embodied between the ratcheting buckle and strap. In an embodiment, the watch comprises a strap including a first strap portion and a second strap portion. The first strap portion comprises a linear rack and a plurality of teeth embedded in the linear rack. The second strap portion coupled to a buckle wherein the buckle comprises a pawl configured to slideably engage up to each of the plurality of teeth of the linear rack as the first strap portion is inserted through a buckle aperture and translated therethrough.

Abstract: A wristwatch is provided incorporating one of a plurality of possible case embodiments, such as, without limitation, mechanical and electronic movements, and a novel ratcheting buckle and corresponding strap, whereby the user may incrementally adjust fitment of the watch via a ratcheting mechanism embodied between the ratcheting buckle and strap. In an embodiment, the watch comprises a strap including a first strap portion and a second strap portion. The first strap portion comprises a linear rack and a plurality of teeth embedded in the linear rack. The second strap portion coupled to a buckle wherein the buckle comprises a pawl configured to slideably engage up to each of the plurality of teeth of the linear rack as the first strap portion is inserted through a buckle aperture and translated therethrough.

Abstract: A system for suspending articles of firearms is disclosed, the system including one or more pockets, one or more magnets disposed in the one or more pockets, and a firearm article wherein the firearm article and the one or more magnets are magnetically coupled so as to form an engagement to at least a portion of the one or more pockets. In one embodiment, a backpack is disclosed having a lumbar compartment disposed between a storage compartment and a user wearing the backpack. The lumber compartment comprises a magnet-containing pocket, the magnet-containing pocket having a magnet configured to suspend a firearm article magnetically coupled therewith. The backpack further includes one or more access points for allowing access to a user for efficiently grabbing a firearm article suspended while wearing the backpack.

Abstract: The disclosure concerns an inner duty belt and related system. The inner duty belt has an inner side and an outer side, and includes a waist portion having a first touch fastener coupled to the outer side, an attachment portion having a connecting element configured to engage with the waist portion, and a flexible portion disposed between the waist portion and the attachment portion. The flexible portion is configured to fold upon convergence of the waist and attachment portions. The flexible portion of the inner duty belt allows the inner duty belt to easily increase and decrease in circumference while engaged with an outer duty belt.

Abstract: The disclosure concerns an inner duty belt and related system. The inner duty belt has an inner side and an outer side, and includes a waist portion having a first touch fastener coupled to the outer side, an attachment portion having a connecting element configured to engage with the waist portion, and a flexible portion disposed between the waist portion and the attachment portion. The flexible portion is configured to fold upon convergence of the waist and attachment portions. The flexible portion of the inner duty belt allows the inner duty belt to easily increase and decrease in circumference while engaged with an outer duty belt.

Abstract: The disclosure concerns an inner duty belt and related system. The inner duty belt has an inner side and an outer side, and includes a waist portion having a first touch fastener coupled to the outer side, an attachment portion having a connecting element configured to engage with the waist portion, and a flexible portion disposed between the waist portion and the attachment portion. The flexible portion is configured to fold upon convergence of the waist and attachment portions. The flexible portion of the inner duty belt allows the inner duty belt to easily increase and decrease in circumference while engaged with an outer duty belt.

Abstract: A multi-component health supplement for improving overall wellness and modulating the immune system is provided as a mixture of N-acetyl-L-cysteine (NAC), quercetin, bromelain, Cordyceps, turmeric extract (curcumin), palmitoylethanolamide (PEA), grape seed extract, green tea extract, elderberry extract, pomegranate extract, and astaxanthin, and optionally one or more vitamins and minerals. Various subcombinations for targeting cellular health, fatigue, oxidative degradation, and other specific health needs are also provided.

Abstract: A wristwatch is provided incorporating one of a plurality of possible case embodiments, such as, without limitation, mechanical and electronic movements, and a novel ratcheting buckle and corresponding strap, whereby the user may incrementally adjust fitment of the watch via a ratcheting mechanism embodied between the ratcheting buckle and strap. In an embodiment, the watch comprises a strap including a first strap portion and a second strap portion. The first strap portion comprises a linear rack and a plurality of teeth embedded in the linear rack. The second strap portion coupled to a buckle wherein the buckle comprises a pawl configured to slideably engage up to each of the plurality of teeth of the linear rack as the first strap portion is inserted through a buckle aperture and translated therethrough.

Abstract: A system for suspending articles of firearms is disclosed, the system including one or more pockets, one or more magnets disposed in the one or more pockets, and a firearm article wherein the firearm article and the one or more magnets are magnetically coupled so as to form an engagement to at least a portion of the one or more pockets. In one embodiment, a backpack is disclosed having a lumbar compartment disposed between a storage compartment and a user wearing the backpack. The lumber compartment comprises a magnet-containing pocket, the magnet-containing pocket having a magnet configured to suspend a firearm article magnetically coupled therewith. The backpack further includes one or more access points for allowing access to a user for efficiently grabbing a firearm article suspended while wearing the backpack.

Abstract: Provided are immediate or prolonged administration of certain potassium ATP (KATP) channel openers, optionally in combination with growth hormone, to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of KATP channel openers that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are methods of co-administering KATP channel openers with other drugs (e.g., in combination with growth hormone) to treat diseases of humans and animals (e.g., Prader-Willi Syndrome (PWS), Smith-Magenis syndrome (SMS), and the like.

Abstract: The disclosure concerns eyeglasses with an integrated magnetic clip for removably attaching the eyeglasses to a wearer's clothing, a vehicular sun visor, or other object. The eyeglasses may embody any wearable optics device, such as, prescription glasses, reading glasses, sunglasses, and the like. In some embodiments, the eyeglasses further include a shield element positioned between a magnetic element of the magnetic clip and a wearer's body for reducing or eliminating magnetic field effects on the body of the wearer.

Abstract: The disclosure concerns eyeglasses with an integrated magnetic clip for removably attaching the eyeglasses to a wearer's clothing, a vehicular sun visor, or other object. The eyeglasses may embody any wearable optics device, such as, prescription glasses, reading glasses, sunglasses, and the like. In some embodiments, the eyeglasses further include a shield element positioned between a magnetic element of the magnetic clip and a wearer's body for reducing or eliminating magnetic field effects on the body of the wearer.

Abstract: The disclosure concerns eyeglasses with an integrated magnetic clip for removably attaching the eyeglasses to a wearer's clothing, a vehicular sun visor, or other object. The eyeglasses may embody any wearable optics device, such as, prescription glasses, reading glasses, sunglasses, and the like. In some embodiments, the eyeglasses further include a shield element positioned between a magnetic element of the magnetic clip and a wearer's body for reducing or eliminating magnetic field effects on the body of the wearer.

Abstract: The disclosure concerns eyeglasses with an integrated magnetic clip for removably attaching the eyeglasses to a wearer's clothing, a vehicular sun visor, or other object. The eyeglasses may embody any wearable optics device, such as, prescription glasses, reading glasses, sunglasses, and the like. In some embodiments, the eyeglasses further include a shield element positioned between a magnetic element of the magnetic clip and a wearer's body for reducing or eliminating magnetic field effects on the body of the wearer.

Abstract: A fluid dispersion assembly comprises a diffusion unit disposed in fluid communication with a fluid container, the assembly being powered by a compressed air source. The diffusion unit at least partially defines a diffusion chamber, and includes a diffusion assembly containing an atomizer assembly which, in combination with the diffusion chamber, generates a fluid dispersion from a mixture of compressed air and an operative fluid, for example, fragrant oils, essential oils, odor neutralizers, disinfectants such as triethylene glycol, air sanitizers, etc.

Abstract: A container is provided. The container has a lid and a tray. The lid has a contiguous array of walls extending therefrom. The tray has a recess for receiving soft food material. The recess is sized to receive the array of walls of the lid. The tray has a contiguous array of ridges corresponding to the array of walls of the lid. A top surface of the ridges of the tray contact a bottom surface of the walls of the lid when mated to form sealed compartments. A sealing mechanism is provided along a perimeter of at least one of the lid and the tray sealing the lid and the tray along perimeters thereof, and restricting separation of the bottom surface of the walls of the lid from the top surface of the ridges of the tray when mated. At least one of the lid and the tray is formed from a flexible material so that the lid and the tray can be partially separated to remove a food portion formed in one of the compartments without breaking all of the seals of the compartments.

Abstract: A ratchet belt system including a belt having a notch strip extending along a portion of the length thereof. The notch strip is formed of a plurality of adjacent notches, each being configured to engage a ratcheting tab of an associated buckle. In an embodiment, the tab is coupled to a release lever that is oriented toward a receptacle portion of the buckle for ergonomically improving the release mechanics. In another embodiment the belt comprises a first notch strip about a first surface of the belt and a second notch strip about a second surface of the belt opposite of the first surface. Other improvements include accessories configured to engage with the ratchet belt system for display and storage thereof.