Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.
Type:
Grant
Filed:
February 15, 2018
Date of Patent:
June 29, 2021
Assignees:
Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes, Establissement Francais Du Sang
Inventors:
Audrey Le Gouellec, Bertrand Toussaint, Jean-Luc Lenormand, David Laurin, Elodie Meynet
Abstract: The present invention relates to a new method for the preservation of blood platelets. In particular, the present invention provides a method which includes submitting the platelets to zeodration carried out at temperatures between 18° C. and 24° C. The dried platelets thus obtained can be preserved at room temperature for long period of time. The invention also provides kits and compositions for using the preserved platelets.
Type:
Application
Filed:
November 26, 2010
Publication date:
March 28, 2013
Applicant:
ESTABLISSEMENT FRANCAIS DU SANG
Inventors:
Francine Rendu, Thibault Donnet, Christian Gachet, Jean-Pierre Cazenave