Abstract: The present invention provides topical compositions containing phosphorylated polyphenols in combination with a topically acceptable carrier. The compositions of the invention provide a means for delayed delivery of the polyphenol to keratinous tissues, such as skin, hair and nails, with enzymes of the keratinous tissue dephosphorylating the polyphenol, and returning it to its native active form. The compositions are particularly useful in the regulation of skin conditions. the phosphorylated stilbene is a phosphorylated resveratrol or a phosphorylated resveratrol derivative.
Type:
Grant
Filed:
June 9, 2009
Date of Patent:
June 18, 2013
Assignees:
Estee Lauder Coordination Center N.V., Ajinomoto Omnichem S.A.
Inventors:
Lieve Declercq, Hugo Corstjens, Daniƫl Maes, Willy Van Brussel, Geert Schelkens
Abstract: The present invention provides topical compositions containing phosphorylated polyphenols in combination with a topically acceptable carrier. The compositions of the invention provide a means for delayed delivery of the polyphenol to keratinous tissues, such as skin, hair and nails, with enzymes of the keratinous tissue dephosphorylating the polyphenol, and returning it to its native active form. The compositions are particularly useful in the regulation of skin conditions.
Type:
Application
Filed:
September 14, 2004
Publication date:
April 24, 2008
Applicants:
AJINOMOTO OMNICHEM S.A., ESTEE LAUDER COORDINATION CENTER N.V.
Inventors:
Lieve Declercq, Hugo Corstjens, Daniel Maes, Willy Van Brussel, Geert Schelkens