Patents Assigned to Etablissement DeClare d'Utilite Publique dit: Institut Pasteur
  • Products of coupling biological substances by covalent bonds
    Patent number: 4925921
    Abstract: This process involves the use of benzoquinone as cross-linking agent in large excess compared with the substance to be activated. The activation reaction is realized in a homogeneous liquid medium. Said process making it possible for example to couple antibodies to enzymes for determining or detecting said antibodies.The process can be used for the determination of antitetanic antibodies in human serum.
    Type: Grant
    Filed: March 24, 1986
    Date of Patent: May 15, 1990
    Assignee: Etablissement Declare d'Utilite Publique Dit. Institut Pasteur
    Inventors: Stratis Avrameas, Therese M. F. Ternynck
  • Process for coupling biological substances by covalent bonds
    Patent number: 4592998
    Abstract: This process involves the use of benzoquinone as cross-linking agent in large excess compared with the substance to be activated. The activation reaction is realized in a homogeneous liquid medium. Said process making it possible for example to couple antibodies to enzymes for determining or detecting said antibodies. The process can be used for the determination of antitetanic antibodies in human serum.
    Type: Grant
    Filed: December 15, 1983
    Date of Patent: June 3, 1986
    Assignee: Etablissement Declare d'Utilite Publique Dit: Institut Pasteur
    Inventors: Stratis Avrameas, Therese M. F. Ternynck
  • Process for coupling biological substances by covalent bonds
    Patent number: 4193982
    Abstract: A process for coupling biological substances by covalent bonds that involves the use of benzoquinone as cross-linking agent in large excess compared with the substance to be activated. The activation reaction is realized in a homogeneous liquid medium. The process makes it possible, for example, to couple antibodies to enzymes for determining or detecting said antibodies.The process can be used for the determination of antitetanic antibodies in human serum.
    Type: Grant
    Filed: December 1, 1976
    Date of Patent: March 18, 1980
    Assignee: Etablissement DeClare d'Utilite Publique dit: Institut Pasteur
    Inventors: Stratis Avrameas, Therese M. F. Ternynck