Patents Assigned to Eth Zuerich
  • Patent number: 12617768
    Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, and R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a radiolabeled ligand.
    Type: Grant
    Filed: May 21, 2024
    Date of Patent: May 5, 2026
    Assignees: HOFFMANN-LA ROCHE INC., ETH ZUERICH
    Inventors: Simon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz, Dieter Muri, Ahmed Haider Wahauib
  • Patent number: 12278270
    Abstract: A method forms a part of a power semiconductor device. The method includes homoepitaxially forming two silicon carbide layers on a first side of a silicon carbide substrate and forming a pattern of pits on a second side of the silicon carbide substrate. The two layers include a buffer layer, on the first side of the silicon carbide substrate, and have a same doping type of the silicon carbide substrate and a doping concentration equal to or greater than 1017 cm?3 in order to increase the quality of at least one subsequent SiC layer. The two layers include an etch stopper layer, being deposited on the buffer layer and has a same doping type as the buffer layer but a lower doping concentration in order to block a trenching process. The pattern of pits, obtained by electrochemical etching, extends completely thorough the silicon carbide substrate and the buffer layer.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: April 15, 2025
    Assignee: ETH Zuerich
    Inventors: Massimo Camarda, Ulrike Grossner
  • Patent number: 12071420
    Abstract: The invention relates to a compound of formula (I) wherein A1, A2, X and R1-R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: August 27, 2024
    Assignees: HOFFMANN-LA ROCHE INC., ETH ZUERICH
    Inventors: Luca Gobbi, Uwe Grether, Julian Kretz, Simon M. Ametamey
  • Patent number: 11999710
    Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, and R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a radiolabeled ligand.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: June 4, 2024
    Assignees: HOFFMANN-LA ROCHE INC., ETH ZUERICH
    Inventors: Simon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz, Dieter Muri, Ahmed Haider Wahauib
  • Patent number: 11992467
    Abstract: The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.
    Type: Grant
    Filed: February 24, 2022
    Date of Patent: May 28, 2024
    Assignees: Universitaet Basel, Eth Zuerich
    Inventors: Michael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
  • Publication number: 20230141082
    Abstract: A diffractometric sensing device for analyzing molecular interactions is described, the diffractometric sensing device comprising a transparent carrier medium, the carrier medium comprising a grating structure (42.1-42.5) with a plurality of consecutive surfaces or lines and a plurality of binding sites arranged thereon, the binding sites being configured to interact with one or more target molecules, wherein the grating structure is configured to diffract a portion of coherent light propagating in the carrier medium so as to produce a constructive interference signal at a light detector (4.1-4.4), the signal being dependent on molecular interactions at or in the vicinity of the binding sites. The invention offers more sensitivity, faster response, miniaturization, easy manufacturing and more applications compared to current diffractometric sensing devices.
    Type: Application
    Filed: February 24, 2021
    Publication date: May 11, 2023
    Applicant: ETH Zuerich
    Inventors: Janos VÖRÖS, Andreas REICHMUTH, Yves BLICKENSTORFER, Andreas FRUTIGER, Katharina KÜBRICH
  • Publication number: 20220202963
    Abstract: The invention provides new radiolabeled monoacylglycerol lipase (MAGL) inhibitors that are useful for medical imaging, such as positron-emission tomography (PET), single-photon emission computed tomography (SPECT) and/or autoradiography.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 30, 2022
    Applicants: Hoffmann-La Roche Inc., ETH ZUERICH
    Inventors: Ludovic COLLIN, Martin EDELMANN, Luca GOBBI, Uwe GRETHER, Thomas HARTUNG, Yingfang HE, Michael HONER, Benoit HORNSPERGER, Carsten KROLL, Linjing MU, Dieter MURI, Fionn O'HARA, Hans RICHTER, Martin RITTER
  • Publication number: 20210115011
    Abstract: The invention relates to a compound of formula (I) wherein A1, A2, X and R1-R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 22, 2021
    Applicants: HOFFMANN-LA ROCHE INC., ETH ZUERICH
    Inventors: Luca Gobbi, Uwe Grether, Julian Kretz, Simon M. Ametamey
  • Publication number: 20210115012
    Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, and R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a radiolabeled ligand.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 22, 2021
    Applicants: HOFFMANN-LA ROCHE INC., ETH ZUERICH
    Inventors: Simon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz, Dieter Muri, Ahmed Haider Wahauib
  • Publication number: 20200147004
    Abstract: The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Applicants: UNIVERSITAET BASEL, ETH ZUERICH
    Inventors: Michael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
  • Patent number: 10551124
    Abstract: A process for producing high-purity magnesium by means of distillation at reduced pressure, characterized in that, the high-purity magnesium condenses in the liquid state, whereby the starting material in the form of a magnesium-containing melt is present together with the upper region of a condensation vessel in the upper region of a retort, whereby the retort consist of a material that releases no volatile impurities into the magnesium steam, whereby the upper region of the retort is brought to a temperature above the boiling point of magnesium, within the limits of two level lines, and is then held constant, such that steam rises from the boiling magnesium-containing metal melt and fills the interior of the upper region of the retort, whereby the steam infiltrating the upper region of the condensation vessel condenses below the lower level line and collects as high-purity melt in the lower region of the condensation vessel, and whereby in order to prevent contaminated melt that drops from the region above
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: February 4, 2020
    Assignee: ETH Zuerich
    Inventors: Christian Wegmann, Joerg Loeffler, Peter Uggowitzer, Minh Becker, Heinrich Feichtinger
  • Patent number: 10273258
    Abstract: The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I): as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: April 30, 2019
    Assignee: ETH ZUERICH
    Inventors: Hansjoerg Gruetzmacher, Georgina Mueller
  • Patent number: 10128439
    Abstract: A phononic transistor can be realized by arranging a row of cantilevered structures with attached magnets, elastically extending upward upon application of a magnetic repulsive force to the magnets. In the extended configuration, the phonons are transmitted from source to drain, while in the flattened configuration the phonons are blocked from transmission. A gate element controls the ON and OFF states of the phononic transistor.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: November 13, 2018
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, ETH ZUERICH
    Inventors: Osama R. Bilal, Chiara Daraio, Andre Foehr
  • Patent number: 10023675
    Abstract: A process for the preparation of a polymer nanoparticle by a photoinduced emulsion polymerization includes preparing an emulsion comprising at least one surfactant, a dispersed phase and a continuous phase. The dispersed phase comprises at least one polymerizable monomer and the continuous phase comprises water and at least one photoinitiator. The at least one polymerizable monomer is polymerized by exposing the emulsion to an electromagnetic radiation having a wavelength so as to induce a generation of radicals from the at least one photoinitiator.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: July 17, 2018
    Assignee: ETH ZUERICH
    Inventors: Hansjoerg Gruetzmacher, Timo Ott
  • Publication number: 20180002357
    Abstract: The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I): as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.
    Type: Application
    Filed: May 24, 2017
    Publication date: January 4, 2018
    Applicant: ETH ZUERICH
    Inventors: Hansjoerg GRUETZMACHER, Georgina MUELLER
  • Patent number: 9701700
    Abstract: The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I): as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: July 11, 2017
    Assignee: ETH ZUERICH
    Inventors: Hansjoerg Gruetzmacher, Georgina Mueller
  • Patent number: 9677151
    Abstract: A process for producing high-purity magnesium by distillation at reduced pressure, which includes providing an apparatus having a retort formed from a material inert with respect to magnesium and an upper region defined by two vertically spaced level lines, a condensation vessel having a lower region and an upper region extending into the upper region of the retort, wherein the retort and condensation vessel are coupled to one another by an opening arranged in the upper region of the condensation vessel; providing a magnesium-containing metal melt to the retort at a level below the gap; and heating and maintaining the upper region of the retort at a temperature above the boiling point of magnesium to fill the retort with steam, thereby delivering a high purity melt into the condensation vessel via the opening.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: June 13, 2017
    Assignee: ETH ZUERICH
    Inventors: Christian Wegmann, Jörg Löffler, Peter Uggowitzer, Minh Becker, Heinrich Feichtinger
  • Publication number: 20160367499
    Abstract: The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.
    Type: Application
    Filed: November 17, 2015
    Publication date: December 22, 2016
    Applicants: UNIVERSITAET BASEL, ETH ZUERICH
    Inventors: Michael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
  • Patent number: 9293531
    Abstract: A tensile strain state in semiconductor components is adjusted. A pretensioned (tensile strain) layer is applied to a substrate (FIG. 1, (A)). Bridge structures (FIG. 1, (B)) are introduced in the layers by lithography and etching. The bridges are connected to the layer on both sides and are thus continuous. The geometric shape of the bridges, formed with a cross-section modulation, is determined by the windows (FIG. 1 (C)) in the layer. When the substrate is etched selectively, the bridge is undercut through the windows. The geometric structuring of the cross-section (FIG. 1, (D)) causes a redistribution of the originally homogeneous strain when the bridges are detached from the substrate, with the larger cross-sections relaxing at the expense of the smaller cross-sections, where the pretension is increased. Only a multiplication of stresses (or strain) originally present in the sample is possible, with the multiplication factor determined by lengths, widths and depths, and/or the relationships thereof.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: March 22, 2016
    Assignees: PAUL SCHERRER INSTITUT, ETH ZUERICH
    Inventors: Jerome Faist, Gustav Schiefler, Hans Christian Sigg, Ralph Spolenak, Martin Süss
  • Patent number: 9181358
    Abstract: A process for the preparation of a polymer nanoparticle by a photoinduced emulsion polymerization includes preparing an emulsion comprising at least one surfactant, a dispersed phase and a continuous phase. The dispersed phase comprises at least one polymerizable monomer and the continuous phase comprises water and at least one photoinitiator. The at least one polymerizable monomer is polymerized by exposing the emulsion to an electromagnetic radiation having a wavelength so as to induce a generation of radicals from the at least one photoinitiator.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: November 10, 2015
    Assignee: ETH ZUERICH
    Inventors: Hansjoerg Gruetzmacher, Timo Ott