Patents Assigned to Eth Zuerich
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Patent number: 12617768Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, and R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a radiolabeled ligand.Type: GrantFiled: May 21, 2024Date of Patent: May 5, 2026Assignees: HOFFMANN-LA ROCHE INC., ETH ZUERICHInventors: Simon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz, Dieter Muri, Ahmed Haider Wahauib
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Patent number: 12278270Abstract: A method forms a part of a power semiconductor device. The method includes homoepitaxially forming two silicon carbide layers on a first side of a silicon carbide substrate and forming a pattern of pits on a second side of the silicon carbide substrate. The two layers include a buffer layer, on the first side of the silicon carbide substrate, and have a same doping type of the silicon carbide substrate and a doping concentration equal to or greater than 1017 cm?3 in order to increase the quality of at least one subsequent SiC layer. The two layers include an etch stopper layer, being deposited on the buffer layer and has a same doping type as the buffer layer but a lower doping concentration in order to block a trenching process. The pattern of pits, obtained by electrochemical etching, extends completely thorough the silicon carbide substrate and the buffer layer.Type: GrantFiled: November 5, 2020Date of Patent: April 15, 2025Assignee: ETH ZuerichInventors: Massimo Camarda, Ulrike Grossner
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Patent number: 12071420Abstract: The invention relates to a compound of formula (I) wherein A1, A2, X and R1-R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.Type: GrantFiled: December 17, 2020Date of Patent: August 27, 2024Assignees: HOFFMANN-LA ROCHE INC., ETH ZUERICHInventors: Luca Gobbi, Uwe Grether, Julian Kretz, Simon M. Ametamey
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Patent number: 11999710Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, and R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a radiolabeled ligand.Type: GrantFiled: December 17, 2020Date of Patent: June 4, 2024Assignees: HOFFMANN-LA ROCHE INC., ETH ZUERICHInventors: Simon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz, Dieter Muri, Ahmed Haider Wahauib
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Patent number: 11992467Abstract: The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.Type: GrantFiled: February 24, 2022Date of Patent: May 28, 2024Assignees: Universitaet Basel, Eth ZuerichInventors: Michael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
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Publication number: 20230141082Abstract: A diffractometric sensing device for analyzing molecular interactions is described, the diffractometric sensing device comprising a transparent carrier medium, the carrier medium comprising a grating structure (42.1-42.5) with a plurality of consecutive surfaces or lines and a plurality of binding sites arranged thereon, the binding sites being configured to interact with one or more target molecules, wherein the grating structure is configured to diffract a portion of coherent light propagating in the carrier medium so as to produce a constructive interference signal at a light detector (4.1-4.4), the signal being dependent on molecular interactions at or in the vicinity of the binding sites. The invention offers more sensitivity, faster response, miniaturization, easy manufacturing and more applications compared to current diffractometric sensing devices.Type: ApplicationFiled: February 24, 2021Publication date: May 11, 2023Applicant: ETH ZuerichInventors: Janos VÖRÖS, Andreas REICHMUTH, Yves BLICKENSTORFER, Andreas FRUTIGER, Katharina KÜBRICH
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Publication number: 20220202963Abstract: The invention provides new radiolabeled monoacylglycerol lipase (MAGL) inhibitors that are useful for medical imaging, such as positron-emission tomography (PET), single-photon emission computed tomography (SPECT) and/or autoradiography.Type: ApplicationFiled: March 11, 2022Publication date: June 30, 2022Applicants: Hoffmann-La Roche Inc., ETH ZUERICHInventors: Ludovic COLLIN, Martin EDELMANN, Luca GOBBI, Uwe GRETHER, Thomas HARTUNG, Yingfang HE, Michael HONER, Benoit HORNSPERGER, Carsten KROLL, Linjing MU, Dieter MURI, Fionn O'HARA, Hans RICHTER, Martin RITTER
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Publication number: 20210115011Abstract: The invention relates to a compound of formula (I) wherein A1, A2, X and R1-R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.Type: ApplicationFiled: December 17, 2020Publication date: April 22, 2021Applicants: HOFFMANN-LA ROCHE INC., ETH ZUERICHInventors: Luca Gobbi, Uwe Grether, Julian Kretz, Simon M. Ametamey
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Publication number: 20210115012Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, and R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a radiolabeled ligand.Type: ApplicationFiled: December 17, 2020Publication date: April 22, 2021Applicants: HOFFMANN-LA ROCHE INC., ETH ZUERICHInventors: Simon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz, Dieter Muri, Ahmed Haider Wahauib
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Publication number: 20200147004Abstract: The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.Type: ApplicationFiled: January 17, 2020Publication date: May 14, 2020Applicants: UNIVERSITAET BASEL, ETH ZUERICHInventors: Michael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
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Patent number: 10551124Abstract: A process for producing high-purity magnesium by means of distillation at reduced pressure, characterized in that, the high-purity magnesium condenses in the liquid state, whereby the starting material in the form of a magnesium-containing melt is present together with the upper region of a condensation vessel in the upper region of a retort, whereby the retort consist of a material that releases no volatile impurities into the magnesium steam, whereby the upper region of the retort is brought to a temperature above the boiling point of magnesium, within the limits of two level lines, and is then held constant, such that steam rises from the boiling magnesium-containing metal melt and fills the interior of the upper region of the retort, whereby the steam infiltrating the upper region of the condensation vessel condenses below the lower level line and collects as high-purity melt in the lower region of the condensation vessel, and whereby in order to prevent contaminated melt that drops from the region aboveType: GrantFiled: May 15, 2017Date of Patent: February 4, 2020Assignee: ETH ZuerichInventors: Christian Wegmann, Joerg Loeffler, Peter Uggowitzer, Minh Becker, Heinrich Feichtinger
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Patent number: 10273258Abstract: The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I): as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.Type: GrantFiled: May 24, 2017Date of Patent: April 30, 2019Assignee: ETH ZUERICHInventors: Hansjoerg Gruetzmacher, Georgina Mueller
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Patent number: 10128439Abstract: A phononic transistor can be realized by arranging a row of cantilevered structures with attached magnets, elastically extending upward upon application of a magnetic repulsive force to the magnets. In the extended configuration, the phonons are transmitted from source to drain, while in the flattened configuration the phonons are blocked from transmission. A gate element controls the ON and OFF states of the phononic transistor.Type: GrantFiled: April 17, 2018Date of Patent: November 13, 2018Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, ETH ZUERICHInventors: Osama R. Bilal, Chiara Daraio, Andre Foehr
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Patent number: 10023675Abstract: A process for the preparation of a polymer nanoparticle by a photoinduced emulsion polymerization includes preparing an emulsion comprising at least one surfactant, a dispersed phase and a continuous phase. The dispersed phase comprises at least one polymerizable monomer and the continuous phase comprises water and at least one photoinitiator. The at least one polymerizable monomer is polymerized by exposing the emulsion to an electromagnetic radiation having a wavelength so as to induce a generation of radicals from the at least one photoinitiator.Type: GrantFiled: October 1, 2015Date of Patent: July 17, 2018Assignee: ETH ZUERICHInventors: Hansjoerg Gruetzmacher, Timo Ott
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Publication number: 20180002357Abstract: The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I): as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.Type: ApplicationFiled: May 24, 2017Publication date: January 4, 2018Applicant: ETH ZUERICHInventors: Hansjoerg GRUETZMACHER, Georgina MUELLER
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Patent number: 9701700Abstract: The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I): as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.Type: GrantFiled: September 30, 2013Date of Patent: July 11, 2017Assignee: ETH ZUERICHInventors: Hansjoerg Gruetzmacher, Georgina Mueller
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Patent number: 9677151Abstract: A process for producing high-purity magnesium by distillation at reduced pressure, which includes providing an apparatus having a retort formed from a material inert with respect to magnesium and an upper region defined by two vertically spaced level lines, a condensation vessel having a lower region and an upper region extending into the upper region of the retort, wherein the retort and condensation vessel are coupled to one another by an opening arranged in the upper region of the condensation vessel; providing a magnesium-containing metal melt to the retort at a level below the gap; and heating and maintaining the upper region of the retort at a temperature above the boiling point of magnesium to fill the retort with steam, thereby delivering a high purity melt into the condensation vessel via the opening.Type: GrantFiled: January 17, 2013Date of Patent: June 13, 2017Assignee: ETH ZUERICHInventors: Christian Wegmann, Jörg Löffler, Peter Uggowitzer, Minh Becker, Heinrich Feichtinger
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Publication number: 20160367499Abstract: The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.Type: ApplicationFiled: November 17, 2015Publication date: December 22, 2016Applicants: UNIVERSITAET BASEL, ETH ZUERICHInventors: Michael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
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Patent number: 9293531Abstract: A tensile strain state in semiconductor components is adjusted. A pretensioned (tensile strain) layer is applied to a substrate (FIG. 1, (A)). Bridge structures (FIG. 1, (B)) are introduced in the layers by lithography and etching. The bridges are connected to the layer on both sides and are thus continuous. The geometric shape of the bridges, formed with a cross-section modulation, is determined by the windows (FIG. 1 (C)) in the layer. When the substrate is etched selectively, the bridge is undercut through the windows. The geometric structuring of the cross-section (FIG. 1, (D)) causes a redistribution of the originally homogeneous strain when the bridges are detached from the substrate, with the larger cross-sections relaxing at the expense of the smaller cross-sections, where the pretension is increased. Only a multiplication of stresses (or strain) originally present in the sample is possible, with the multiplication factor determined by lengths, widths and depths, and/or the relationships thereof.Type: GrantFiled: May 4, 2012Date of Patent: March 22, 2016Assignees: PAUL SCHERRER INSTITUT, ETH ZUERICHInventors: Jerome Faist, Gustav Schiefler, Hans Christian Sigg, Ralph Spolenak, Martin Süss
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Patent number: 9181358Abstract: A process for the preparation of a polymer nanoparticle by a photoinduced emulsion polymerization includes preparing an emulsion comprising at least one surfactant, a dispersed phase and a continuous phase. The dispersed phase comprises at least one polymerizable monomer and the continuous phase comprises water and at least one photoinitiator. The at least one polymerizable monomer is polymerized by exposing the emulsion to an electromagnetic radiation having a wavelength so as to induce a generation of radicals from the at least one photoinitiator.Type: GrantFiled: April 16, 2010Date of Patent: November 10, 2015Assignee: ETH ZUERICHInventors: Hansjoerg Gruetzmacher, Timo Ott