Abstract: The present invention relates to the field of medicine, specifically the field of bacterial infection and treatment thereof.

Abstract: The present invention relates to wearable device (1) adapted to detect contacts of fingers (F) on a surface (S), and to identify the responsible finger. It comprises move sensors adapted to collect the vibrations resulting from the contact of the fingers on a surface. It comprises a memory comprising reference vibration profiles (T), corresponding to the impact of at least one finger (F) of a user (U) to a surface (S). A computing unit (32) is configured allows to identify the finger responsible for the impact sensed by the move sensors (10, 10a, 10b). The invention further relates to a manufacturing process of such a device and to a method of sensing the contact of a finger on a surface.

Abstract: A wireless communication system can include an antenna and an equalization system. The antenna can be configured to wirelessly receive a data signal from a user equipment (UE). The equalization system can be configured to compensate for distortion incurred by the data signal during propagation. The equalization system can include a set of multiplier circuits. Each multiplier circuit can include a first input, a second input, a multiplier device, and a management circuit. The first input can receive a first input signal that corresponds to the data signal. The second input can receive a second input signal that corresponds to a weighting value assigned to a channel associated with the antenna. The multiplier device can be enabled or disabled. When enabled, the multiplier device can be configured to perform a multiplication operation on the first input signal and the second input signal. When disabled, the multiplier circuit may not perform the multiplication operation.

Abstract: Provided herein, in some embodiments, are engineered nucleic acid targeting vectors that include a sequence of interest flanked by homology arms, each homology arm comprising a sequence homologous to a sequence in a safe harbor site in the human genome in any one of the following loci: 1q31, 3p24, 7q35, and Xq21. Also provided herein are methods of using and compositions the comprising engineered nucleic acid targeting vectors.

Abstract: A method for laterally confining neutral excitons in a semiconductor layer structure (11) of a solid-state device comprises creating an inhomogeneous electric field (F) in the semiconductor layer structure (11), the electric field (F) having an in-plane field component (Fx) whose magnitude varies along at least at least one confinement direction (x) in the device plane, the magnitude of the in-plane field component (Fx) having a maximum along the confinement direction (x). In this manner a lateral confining potential (V(x)) for neutral excitons is caused around the maximum. The solid-state device (10) is irradiated with light to create neutral excitons in the semiconductor layer structure (11). The neutral excitons are laterally confined along the confinement direction (x) by the lateral confining potential (V(x)).

Abstract: Thin films of lithium-containing materials and methods for fabricating them are generally described. In some embodiments, the formation of a first vapor is induced from a first target and the formation of a second vapor is induced from a second target, resulting in the formation of a thin film. In some embodiments, at least a portion of the formation of the first vapor and the formation of the second vapor occurs under vacuum conditions. In some embodiments, the thin film has a relatively high ionic conductivity, mixed ionic/electronic conductivity, or other properties beneficial for applications such as active electrode materials or solid-state electrolytes.

Abstract: Slurry for the coating of a cathode of lithium ion battery, wherein the slurry consists of a solid fraction and of a solvent/dispersant fraction, wherein the solid fraction consists of: (a) 90-95% by weight of a lithium metal oxide based particulate electrochemically activatable material; (b) 2-6% by weight of an acidic polyacrylate or polymethacrylate binder material; (c) 2-6% by weight of conductive particulate carbon; (d) 0-2% by weight further additives different from (a)-(c) wherein the sum of (a)-(d) make up 100% of the solid fraction and wherein the solvent/dispersant fraction consists of: (A) 5-25% by weight of an organic alcoholic solvent/dispersant; (B) 5-30% by weight of water (C) 0-5% by weight of solvents/dispersants different from (A) and (B) wherein the percentages of the solvent/dispersant fraction are relative to the 100% solids fraction.

Abstract: The present invention comprises a fish guidance rack (2) for use in a fish guidance system in a watercourse (W) at a run-of-river hydropower plant or a water intake. The rack comprises a series of vertical bars (1) mounted on a rack frame (7) along a longitudinal axis (L) of the rack between a first end (5) of the rack and a second end (6) of the rack. The rack comprises bars with a hydrodynamic curved form, and a generally increasing inter-bar spacing (sb) in the downstream direction.

Abstract: An implantable sensor (1) for determining at least one parameter, in particular a physical parameter, comprises a sensor body (3). The sensor body (3) is responsive to the at least one parameter and is configured to yield at least one response signal (SR) upon an interrogation of the sensor body (3) with at least one interrogation signal (SI) comprising acoustic waves. The at least one response signal (SR) is associated with the at least one parameter. The sensor body (3) comprises or consists of at least one material having an ordered structure (4). The at least one response signal (SR) is associated with one or more bulk effects of the at least one material having an ordered structure (4).

Abstract: A fabrication method of an elastomer breath structure includes the steps of applying a liquid elastomer onto a substrate an initial curing of the liquid elastomer on the substrate partially into a partially cured polymer, condensation of water droplets from the environment onto the partially cured polymer, and finishing curing of the partially cured polymer with parallel removal of the water droplets creating surface dimples on the cured elastomer.

Abstract: A system and a method for training a model to be used for semantic segmentation of images, comprising: a—obtaining (S01) a first plurality of foggy images (101), b—training (S02) a classification model for estimating fog density, c—classifying (S03) a second plurality of images (101) having light fog, d—obtaining (S04) a third plurality of foggy images (103) having light fog, e—training (S05) a semantic segmentation model using the third plurality of foggy images, f—applying (S06) the semantic segmentation model to the second plurality of foggy (102) images to obtain semantic segmentations (102?), g—obtaining (S07) a fourth plurality of foggy images (104) having dense fog, h—training (S08) using the previously obtained foggy images.

Abstract: The invention relates to a chimeric antigen-receptor polypeptide heterodimer comprising two polypeptides, wherein the first contains an extracellular part of the major histocompatibility complex I alpha chain and the second contains a 32-microglobulin domain, or the first contains an extracellular part of the major histocompatibility complex II alpha chain and the second contains a major histocompatibility complex II beta chain. One of the polypeptides further contains a transmembrane domain, a hinge region and an intracellular domain of the T cell receptor alpha chain and the other one contains a transmembrane domain, a hinge region and an intracellular domain of the T cell receptor beta chain, and additionally an antigen-peptide covalently linked to said extracellular MHC domain. The invention further relates to a method for the identification of a TCR recognizable peptide sequence making use of the heterodimer of the invention.

Abstract: The invention relates to a method for producing a solid construction material which is preferably substantially free of hydraulic binder, comprising the steps of: a. extracting a mineral fraction comprising argillaceous particles of a soil; b. optionally adjusting the particle size of the mineral fraction extracted, in particular in relation to its clay, sand, gravel or loam content, if necessary; c. preparing a first aqueous grout from at least one part of the mineral fraction extracted and optionally adjusted in terms of particle size; d. adding a dispersant that can disperse the argillaceous particles in the first grout in order to obtain a second aqueous grout, e. adding a coagulant that can promote the agglomeration of the argillaceous particles in the second grout in order to obtain an aqueous construction material grout; f introducing the construction material grout into a formwork; and g.

Abstract: The invention relates to a product having a foam structure with a set ratio of gas pores open to the product surface and closed to the product surface. The invention also relates to a method with four embodiments according to the invention for the defined mechanical opening of closed foam pores. Furthermore, the invention relates to a device having four embodiments according to the invention for the defined mechanical opening of closed foam pores. The invention also relates to the use of products designed according to the invention as meat analogs or plant protein-based textured multiphase foods, more particularly vegetable or fruit composites. Particular advantages of the invention relate to the targeted influencing of the deformation and texture properties of foamed products and their accessibility from the outside for quick and easy filling of the open pores with fluid systems which introduce additional functionalities into the product.

Abstract: The invention relates to a product having a foam structure with foam pores which are partially open to the surface and are filled, partially or completely, with a fluid. The invention further relates to a method having embodiments for filling open foam pores in a defined manner. The invention also relates to a device having embodiments for filling open foam pores in a defined manner. The invention furthermore relates to the use of the foam products designed and filled according to the invention as main components for plant protein-based meat analogs. Particular advantages of the invention are the simplified multifunctionality of the products according to the invention in terms of their sensory and nutritional properties for adaptation to preferences and needs of certain target groups including individual customization.

Abstract: The present invention relates to the use of plant extracts from the genus Daphne for the cosmetic treatment of the skin and to cosmetic preparations which comprise extracts of Daphne giraldii and/or Daphne gnidium or other members of the genus Daphne containing daphnetoxin and/or other daphnane diterpenoids for skin treatment. The plant extracts and cosmetic preparations are particularly useful for stimulation of the lymphatic system.

Abstract: A soft wearable muscle assisting device has at least a wearable body interface and attached thereon elements of active and passive components, adapted to together assist a user in changing or maintaining a position of a first body part articulated to a second body part. The wearable body interface comprises at least two gar-ment portions. The active and passive components comprise at least one actively powered element. The passive components comprise at least a first passive component and a second passive component that both extend between the at least two garment components and comprise elastic material for storing energy provided by the user and/or by the at least one actively powered element. The first and a second passive components are arranged on opposite sides of a joint of the body.

Abstract: The invention relates to an expression system for controlling a network in a cell, wherein the network comprises an actuator molecule and an output molecule, wherein the output molecule is positively or negatively regulated by the actuator molecule, wherein the expression system comprises a recombinant gene encoding a first controller molecule, wherein the first controller molecule positively or negatively regulates the actuator molecule. The invention further relates to a cell comprising the expression system, to a cell for use as a medicament and to a method for controlling a network in a cell.

Abstract: The invention relates to a device (1) for generating droplets (30) comprising a plurality of channels (20), wherein each channel (20) extends from an inlet (201) along a respective longitudinal axis (L) to an outlet (202), wherein said device (1) comprises a plurality of layers (10) of a substrate material arranged in a stack (100), wherein each layer (10) comprises a first side (101) and a second side (102) facing away from each other, and wherein said first side (101) of each layer (10) comprises a plurality of grooves (103), wherein said channels (20) are formed by said grooves (103) of said first side (101) of a respective layer (10) of said stack (100) and said second side (102) of a respective adjacent layer (10) of said stack (100). The invention further relates to a method for generating droplets (30) and a fabrication method of the device (1).

Abstract: A modeling engine generates a prediction model that quantifies and predicts secondary dynamics associated with the face of a performer enacting a performance. The modeling engine generates a set of geometric representations that represents the face of the performer enacting different facial expressions under a range of loading conditions. For a given facial expression and specific loading condition, the modeling engine trains a Machine Learning model to predict how soft tissue regions of the face of the performer change in response to external forces applied to the performer during the performance. The modeling engine combines different expression models associated with different facial expressions to generate a prediction model. The prediction model can be used to predict and remove secondary dynamics from a given geometric representation of a performance or to generate and add secondary dynamics to a given geometric representation of a performance.