Abstract: Techniques are disclosed for generating autostereoscopic video content. A multiscopic video frame is received that includes a first image and a second image. The first and second images are analyzed to determine a set of image characteristics. A mapping function is determined based on the set of image characteristics. At least a third image is generated based on the mapping function and added to the multiscopic video frame.

Abstract: The invention relates to a polymer structure (1) formed by at least a polymer, wherein said structure (1) comprises a volume (2) and a surface (3), wherein said polymer comprises a plurality of polymer chains connected by linkings, characterized by a linking density, wherein said linking density increases, particularly monotonously, from the surface (3) into the volume (2) of the polymer structure (1).

Abstract: The present invention relates to a method to reprogramming pluripotent stem cells (PSCs) by epigenetic conditioning and metabolic reprogramming into p PSCs with highly controllable biological functions, the cells obtained by said method as well as methods of using said cells.

Abstract: The invention relates to a method, a device and a system for producing particularly a hydrogel (200) and for controlling an enzymatically catalysed formation of a covalent bond in a solution, wherein said covalent bond is formed between a first compound (20) comprising a first moiety (21) and a second compound (22) comprising a second moiety (23), wherein the first and the second moiety (21, 23) are a substrate of an enzyme wherein said enzyme catalyzes the formation of a covalent bond between the first and the second moiety (21, 23), and wherein a voltage is applied to the solution for spatially controlling said formation, wherein said voltage is adjusted such that it induces electrolysis of said solution.

Abstract: A method for the production of biodegradable nanoparticles with an average particle size of less than 400 nm. In a first step, a macromonomer is prepared in a ring opening polymerization process between a hydrophilic acrylate compound (A) as an initiator and hydrophobic cyclic monomers (B), wherein the macromonomer comprises at least two repetitive units based on the cyclic monomer. In a second step, this macromonomer or a mixture of macromonomers and/or commercial biocompatible monomers is polymerized, e.g. in a starved, miniemulsion or emulsion radical polymerization in water in the presence of a surfactant to the nanoparticle without necessitating additional subsequent steps for the actual production of the nanoparticles. The correspondingly made nanoparticles and uses thereof also are disclosed.

Abstract: A method for the self-assembled production of a topographically surface structured cellulose element. First, a mold is provided having on one side a first surface which is in a complementary manner topographically structured and which is permeable to oxygen. Next, a liquid growth medium containing cellulose producing bacteria is provided. Then, the mold is placed to form a interface such that the side of the mold with the first surface is in direct contact with the liquid growth medium, and an opposite side is facing air or a specifically provided oxygen containing gas surrounding. This allows bacteria to be produced and deposit cellulose on the first surface and developing on the interface a surface structured surface complementary thereto, until a cellulose layer with a thickness of the element of at least 0.3 mm is formed. Finally; the element is removed from the mold.

Abstract: The invention is a wearable mechatronic posture assisting device comprising an upper support (10) for connecting to the thigh of a person, a lower support (20) for connecting to the shank of the person and a joint (28) pivotably connecting both supports (10, 20), and a damper (30) with connectors (31a, 32a) for pivotably connecting the damper (30) to the supports (10, 20). The damper (30) is designed to linearly damp the pivot of the joint (28). The damper (30) comprises a control means allowing a locking and a drive state (101, 103) of the damper (30).

Abstract: Provided herein are methods and compositions for the treatment of metabolic disorders. Also provided herein are methods and compositions for the reduction of blood glucose level, the reduction of gluceoneogenesis, the improvement of insulin resistance and the reduction of plasma cholesterol level. In certain embodiments, the methods comprise inhibiting the activity of miR-103. In certain embodiments, the methods comprise inhibiting the activity of miR-107. In certain embodiments, the activity of both miR-103 and miR-107 is inhibited. In certain embodiments, such methods comprise administering a compound comprising an oligonucleotide targeted to a microRNA.

Abstract: Feedback control of combustion in a gas diesel dual-fuel engine (20), based on the measured cylinder pressure, has been invented. The center of combustion and pressure rise rate is controlled by manipulating the start of diesel injection and duration of diesel injection. Measurements of transient engine operation show, that the proposed controller is able to control the center of combustion and the maximum pressure rise rate. The influence of changing intake manifold pressure, changing exhaust gas recirculation rate and changing air-fuel ratio can be compensated by the controller (10). Steady state measurements show that the gas diesel dual fuel engine reaches efficiencies around 40% with stoichiometric air-fuel ratio and diesel ratios below 5%. The results have been obtained on a slightly modified production type common-rail diesel engine with four cylinders and a displacement volume of 2 litres.

Abstract: A camera of an apparatus for determining a set of model data describing an object in three dimensions from two-dimensional image frames taken from the object, is responsible for taking the two-dimensional image frames from the object. A processor of the apparatus is adapted to determine an interim set of model data representing a portion of the object which is derivable from a set of image frames supplied by the camera so far.

Abstract: Systems and methods to generate stereoscopic panoramas obtain images based on captured images. The obtained images may be processed and/or preprocessed, for example to compensate for perspective distortion caused by the non-ideal camera orientation during capturing, to reduce vertical parallax, to align adjacent images, and/or to reduce rotational and/or positional drift between adjacent images. The obtained images may be used for interpolating virtual in-between images on the fly to reduce visible artifacts in the resulting panorama. Obtained and/or interpolated images (or image fragments) may be stitched together to form a stereoscopic panorama.

Abstract: The invention relates to a method for the determination of a cancer diagnostic/therapeutic biomarker assay and drug-targets including the following steps: (a) identification of potential candidate protein/peptide biomarkers and drug-targets based on the measurement of protein/peptide constituent concentrations in tissue sample proteomes as well as serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and qualitatively selecting as potential candidate protein/peptide biomarkers those which show a pronounced differential behavior between healthy and cancerous sample proteomes; (b) optional verification of the potential candidate protein/peptide biomarkers as identified in step (a) by quantitative mass spectrometric measurement of the potential candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from health

Abstract: Approaches are described for tone-mapping an image frame in a sequence of image frames. A tone-mapping pipeline applies a spatiotemporal filter to each pixel of the image frame, based on a forward optical flow and a backward optical flow, to produce a base layer image. The tone-mapping pipeline applies a temporal filter to each pixel of the image frame, based on the forward and backward optical flows, to produce a temporally filtered frame. The tone-mapping pipeline produces a detail layer image based on the base layer image and the temporally filtered frame. The tone-mapping pipeline produces a detail layer image based on the base layer image and the temporally filtered frame. The tone-mapping pipeline applies a tone curve to the base and detail layer images to produce a tone-mapped base and detail layer image, respectively, and combines the tone-mapped base and detail layer images to produce a tone-mapped image frame.

Abstract: Approaches are described for filtering a first image frame in a sequence of image frames. A tone-mapping pipeline applies a spatiotemporal filter to each pixel of the first image frame, based on a forward optical flow and a backward optical flow, to produce a base layer image. The tone-mapping pipeline applies a temporal filter to each pixel of the first image frame, based on the forward optical flow and the backward optical flow, to produce a temporally filtered frame. The tone-mapping pipeline produces a detail layer image based on the base layer image and the temporally filtered frame.

Abstract: The invention relates to a compound described by a general formula (1), wherein each X independently can be OPO32?, OPSO22? or OSO3?; R1 comprises a solubility function such as a polyethylene glycol moiety and each X independently can be OPO32?, OPSO22?, ? or OSO3?; and Z is an alkyl chain comprising 1 to 3 carbon and/or hetero atoms. The invention further relates to polysulfate derivatives or mixed polyphosphate/sulphate derivatives of six-membered cyclic polyols for use in the therapy of infection by Clostridium difficile.

Abstract: System, method, and computer program product to perform an operation, comprising sampling a plurality of points and a plurality of segments of a curve on a surface of a three-dimensional model, storing each sampled point as a respective vertex of a plurality of vertices and each sampled segment as a respective half-edge in a curve network of the model surface, upon determining that a first half-edge and a second half-edge connect two of the plurality of vertices, generating a first halfchain connecting the first half-edge and the second half-edge, wherein each connected vertex comprises either a corner or an open endpoint, and upon determining that three consecutive halfchains form a loop comprising at least three corners, generating a first patch for a space enclosed by the loop, wherein the first patch is represented as a quad mesh with a respective set of vertices, faces, and half-edges.

Abstract: Systems and methods are disclosed for quantitating detectable compounds of a sample. Sample product ion spectra are received for each mass selection window for each time step. The received sample product ion spectra are searched for the presence of known compounds of interest with known product ion spectra by retrieving the known product ion spectra from a library, retrieving the sample product ion spectra corresponding to the precursor mass selection window expected to contain a precursor ion corresponding to the known product ion spectra, generating product ion traces in time for the sample product ion spectra for the known product ion spectra, calculating a score for the product ion traces and product ion spectra that represents how well known product ions and sample product ions match, and calculating a quantitative value for the known compound from the product ion traces when the score exceeds a threshold value.

Abstract: Systems and methods are disclosed for identifying detectable compounds of a sample. Sample product ion spectra are received for each mass selection window of precursor mass selection windows for each time step. The received sample product ion spectra are searched for the presence of known compounds of interest with known product ion spectra by retrieving a known product ion spectrum from a library, retrieving the sample product ion spectra corresponding to the precursor mass selection window expected to contain a precursor ion corresponding to the known product ion spectrum, generating product ion traces in time for the retrieved sample product ion spectra, calculating a score for the product ion traces and the retrieved sample product ion spectra that represents how well the retrieved sample product ion spectra and the known product ion spectrum match, and confirming the identity of a precursor ion using the score.

Abstract: The present invention relates to the manufacturing gelatin fibers comprising the steps of: (a) preparing a two-phase composition as defined in the claims, (b) spinning the lower phase of said composition, (c) stretching the obtained fiber and (d) optional finishing steps; to new gelatin fibers and to the use thereof.

Abstract: Mixed reality simulation in general, and more specifically to mixed reality simulation devices and systems for training purposes, for example in the medical field, may be provided. For example, a mixed reality simulation method for rendering on a display a mixed reality scenario of a virtual environment adapted to a physical environment, may comprise acquiring, with a sensor, a position of a physical environment object; identifying a mismatch between a physical environment surface and a virtual environment surface, the mismatch depending on the physical environment object position and a mixed reality scenario parameter; and computing a mapping displacement for a virtual environment surface based on the identified mismatch.