Patents Assigned to Ethicon, Inc.
  • Patent number: 11123397
    Abstract: Provided are pharmaceutical foam compositions comprising a peptone, a peptide hydrolysate or an enzymatically-hydrolyzed protein prepared by enzymatic hydrolysis of a full-length protein; methods of preparation and uses thereof.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 21, 2021
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Tamar Auerbach-Nevo, Ashley Deanglis, Israel Nur
  • Patent number: 11118025
    Abstract: Novel absorbable foams, lyophilizing solutions, and lyophilizing and annealing processes are disclosed. The foams are made from copolymers of glycolide and epsilon-caprolactone. The foams are useful in or as implantable medical devices.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: September 14, 2021
    Assignee: Ethicon, Inc.
    Inventors: Jackie Donners, Marc Wisnudel, Mark Timmer
  • Patent number: 11103237
    Abstract: A suture needle container includes a receptacle having a proximal end with an opening and a closed distal end. A hollow mandrel is disposed inside the receptacle. The mandrel projects from the closed distal end toward the opening at the proximal end of the receptacle. The mandrel includes a tubular wall having a proximal end aligned with the proximal end of the receptacle and a distal end connected with the closed distal end of the receptacle. An elongated slot is formed in the tubular wall. A suture needle is disposed within the elongated slot. A suture is secured to the proximal end of the suture needle and wrapped around the hollow mandrel. A cover closes the opening at the proximal end of the receptacle for sealing the suture needle and the suture inside the receptacle for maintaining a sterile environment inside the receptacle.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: August 31, 2021
    Assignee: Ethicon, Inc.
    Inventors: Christophe Vailhe, Doug Souls
  • Patent number: 11083822
    Abstract: Combination cellulose materials and methods of making and using these materials. The combination material includes a first cellulosic material and a second cellulosic material.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: August 10, 2021
    Assignee: Ethicon, Inc.
    Inventors: Daniel J. Smith, Christophe Vailhe
  • Patent number: 11058792
    Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: July 13, 2021
    Assignee: Ethicon, Inc.
    Inventors: Dennis D. Jamiolkowski, Christopher DeFelice, Sasa Andjelic, Brian M. Kelly, Marc Wisnudel, Daniel Steiger, Gaoyuan Gavin Chen
  • Patent number: 11054343
    Abstract: A system for testing substrates includes a first elongated member including an outer end, an inner end, an outer surface that extends between the outer and inner ends, and a concave surface at the inner end, and a second elongated member including an outer end, an inner end, an outer surface that extends between the outer and inner ends of the second elongated member, and a convex surface at the inner end of the second elongated member that opposes the concave surface at the inner end of the first elongated member. A joint interconnects the first and second elongated members for guiding sliding movement of the concave surface of the first elongated member over the convex surface of the second elongated member between extended and flexed positions. A first clamping assembly is coupled with the first elongated member and at least one first clamping assembly spring normally urges the first clamping assembly away from the inner end of the first elongated member.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: July 6, 2021
    Assignee: Ethicon, Inc.
    Inventors: Amitha Anand Kumar, Glenn R. Cook, Julian Quintero, Shane A. Lacy
  • Patent number: 11045588
    Abstract: Provided is an antimicrobial composition comprised of at least one degradation product of oxidized cellulose (OC), such as oxidized regenerate cellulose (ORC), and minocycline, methods of preparation thereof and uses thereof.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: June 29, 2021
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Eve Montia, Dwayne Looney, Theresa Scheuble, Ronen Eavri, Roi Mashiach
  • Patent number: 11028222
    Abstract: The present invention is directed methods of making absorbable poly(p-dioxanone) pellets by melt polymerization of p-dioxanone conducted in a single reactor with a temperature regulator by charging a melt reactor with a mixture of p-dioxanone (PDO) monomer, initiator, catalyst, and optionally a dye; melt polymerizing the mixture in the melt reactor with sufficient agitation of the mixture to allow complete mixing of the monomer and for sufficient time to form a PDO polymer product having an unreacted PDO monomer content of at least 65 mole percent; placing the PDO polymer product under a vacuum to remove at least portion of unreacted PDO; discharging the PDO polymer product from the melt reactor directly into an in-line, underwater pelletizer to produce undried PDO pellets, collecting the undried PDO pellets, and storing the collected PDO pellets in the freezer or a vacuum chamber prior to drying.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: June 8, 2021
    Assignee: Ethicon, Inc.
    Inventors: Sasa Andjelic, Brian M. Kelly, Marc Wisnudel
  • Patent number: 11020100
    Abstract: Provided herein are systems for preparing and delivering fibrin sealant to a surface and methods of use thereof. In one embodiment, the system comprises: a. a quantity of a liquid mixture disposed within a container, the mixture comprising: I. fibrin or II. fibrinogen and Factor II; and b. a resin bed disposed within a vessel, the vessel capable of being in fluid communication with the container, wherein when in fluid communication, passage of the mixture through the vessel results in modification of the concentration of small molecules inhibitor(s) and/or inducer(s) within the mixture, favoring fibrin clot formation.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: June 1, 2021
    Assignees: Omrix Biopharmaceuticals, Ltd., Ethicon, Inc.
    Inventors: Ashley DeAnglis, Yair Pilpel, Yuri Zherdev, Sivan Doron, Lior Erez
  • Publication number: 20210146015
    Abstract: A novel two-step process for batch coating surgical needles with cross-linked silicone coatings is disclosed. The surgical needles are cured using a two-step process. The coatings on the needles are partially cured in the first step and mechanically separated. The coatings on the needles are then fully cured in the second step.
    Type: Application
    Filed: November 24, 2020
    Publication date: May 20, 2021
    Applicant: Ethicon, Inc.
    Inventor: Duan Li Ou
  • Patent number: 11007296
    Abstract: A drug-eluting self-retaining suture comprises a filament, a plurality of retainers, and a drug impregnated in or coated on the filament. The shape and distribution of retainers modifies the in vivo release kinetics of the drug. The drug release kinetics may be modified uniformly or region by region. The self-retaining suture may for example be used for reattaching severed nerves and release nerve growth factor or other regeneration accelerating agents into the region of the nerve injury.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: May 18, 2021
    Assignees: Ethicon, Inc., Ethicon, LLC, Tissuegen, Inc.
    Inventors: Jeffrey M. Gross, Lev Drubetsky, Alexander Naimagon, Rui Avelar, William L. D'Agostino, Kevin Don Nelson, Brent B. Crow, Nickolas B. Griffin
  • Patent number: 11006937
    Abstract: The present invention is directed to a device for delivering a sealant to a tissue, comprising a sealant compartment, a cooling gas compartment, and a heater, all disposed inside a unified housing; with heater configured for rendering the sealant liquid or semi-liquid or molten and flowable; with sealant compartment configured for expressing the sealant in a flowable form from device via an exit nozzle; with gas compartment configured for expressing a cooling gas via a gas expression port; with exit nozzle and gas expression port co-directed into the same direction.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: May 18, 2021
    Assignee: Ethicon, Inc.
    Inventors: Nir I. Nativ, Thomas C. Weindl, Leo B. Kriksunov
  • Patent number: 11007301
    Abstract: The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: May 18, 2021
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Erez Ilan, Omri Faingold, Nataly Freizus, Ronen Eavri, Dwayne Looney, Sridevi Dhanaraj, James Galloway, Walter Danker
  • Patent number: 11007299
    Abstract: The present invention is directed to a hemostatic semi-solid paste material comprising a bioabsorbable carrier hemostatic material; and a supplemental hemostatic agent; wherein the paste material has an elongated form extending along a lengthwise axis with an aspect ratio of at least 3; wherein the paste is self-supporting and syringe extrudable; and wherein the supplemental hemostatic agent has a non-homogenous distribution profile across a cross-section taken across the lengthwise axis. In another aspect, the present invention relates to devices for forming and expressing the hemostatic material.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: May 18, 2021
    Assignee: Ethicon, Inc.
    Inventors: Yi-Lan Wang, Leo B. Kriksunov
  • Patent number: 11007300
    Abstract: The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: May 18, 2021
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Erez Ilan, Omri Faingold, Nataly Freizus, Ronen Eavri, Dwayne Looney, Sridevi Dhanaraj, James Galloway, Walter Danker
  • Patent number: 11000635
    Abstract: Disclosed are compositions comprised of Oxidized Cellulose (OC), such as oxidized regenerated cellulose (ORC), and an antibiotic comprised of minocycline, methods of preparation thereof and uses thereof.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: May 11, 2021
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Eve Montia, Dwayne Looney, Theresa Scheuble, Ronen Eavri, Roi Mashiach
  • Patent number: 11000280
    Abstract: Novel recessed surgical fastening devices are disclosed. The fastening devices have a compressible member and a fastening element disposed at least partially within the compressible member. The fastening element has at least one tissue engagement member that is extensible through the compressible member to engage tissue when a force is applied to the fastening device.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: May 11, 2021
    Assignee: Ethicon, Inc.
    Inventors: Robert J. Tannhauser, Emil Richard Skula
  • Patent number: 11000271
    Abstract: A method of attaching a surgical suture to a needle and testing the attachment includes dispensing a length of suture from a spool by using a first suture gripper, and using a surgical needle gripper for holding a surgical needle stationary. A leading end of the suture is inserted into and attached to a receiving end of the surgical needle. A second suture gripper is located between the first suture gripper and the spool. After the second suture gripper is closed for gripping the suture, the second suture gripper is advanced downstream toward the surgical needle to reduce the tension on the suture. The tension on the suture is reduced by moving the second suture gripper a pre-determined distance. The first suture gripper is opened for releasing the suture and the first suture gripper is moved toward the suture spool for re-grasping the suture at a location between the second gripper and the suture spool.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: May 11, 2021
    Assignee: Ethicon, Inc.
    Inventors: Timothy P. Lenihan, Yasemar Perez
  • Patent number: D920512
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: May 25, 2021
    Assignee: Ethicon, Inc.
    Inventor: Frank Richard Cichocki, Jr.
  • Patent number: D930819
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: September 14, 2021
    Assignee: Ethicon, Inc.
    Inventors: Jianxin Guo, Jared Schneider, Simon Cohn