Patents Assigned to Etubics Corporation
  • Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
    Patent number: 11826417
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: November 14, 2022
    Date of Patent: November 28, 2023
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle, III
  • Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
    Patent number: 11529408
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: December 20, 2022
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle, III
  • Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
    Patent number: 11504423
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: November 22, 2022
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle, III
  • Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
    Patent number: 11389521
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: July 19, 2022
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle, III
  • Breast cancer vaccines and methods of use thereof
    Patent number: 11376316
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: July 5, 2022
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle
  • HPV vaccines and methods of use thereof
    Patent number: 11369673
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: June 28, 2022
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle
  • Methods and compositions for combination immunotherapy
    Patent number: 11352642
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: June 7, 2022
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Elizabeth Gabitzsch, Yvette Latchman, Adrian Rice
  • Sequential administration of a replication defective adenovirus vector in vaccination protocols
    Patent number: 11344613
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: May 31, 2022
    Assignee: Etubics Corporation
    Inventors: Joseph P. Balint, Frank R. Jones, Richard B. Gayle, III
  • Combination immunotherapies comprising IL-15 superagonists
    Patent number: 11304998
    Abstract: Methods and compositions for generating enhanced immune responses using adenovirus vectors that allow for multiple vaccinations in combination with an IL-15 superagonist complex in subjects in need thereof are provided.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: April 19, 2022
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Adrian Rice, Elizabeth Gabitzsch, Yvette Latchman, Joseph Balint
  • Methods and compositions for combination immunotherapy
    Patent number: 11149087
    Abstract: Methods and compositions for generating immune responses using adenovirus vectors that allow multiple vaccinations or in combination with other therapy and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: October 19, 2021
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Elizabeth Gabitzsch, Yvette Latchman, Adrian Rice
  • Compositions and methods for tumor vaccination and immunotherapy involving HER antigens
    Patent number: 11116827
    Abstract: In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof. In particular embodiments, there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof, that allow for vaccinations in individuals with preexisting immunity to adenovirus.
    Type: Grant
    Filed: June 2, 2018
    Date of Patent: September 14, 2021
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Joseph Balint, Elizabeth Gabitzsch
  • Compositions and methods for alphavirus vaccination
    Patent number: 11104916
    Abstract: Compositions of a recombinant adenovirus based vector vaccine containing one or more alphavirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate broad based immune responses against alphaviruses are also described. Compositions described herein allow for vaccinations in individuals with preexisting immunity to adenovirus.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: August 31, 2021
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Joseph Balint, Adrian Rice, Yvette Latchman, Elizabeth Gabitzsch
  • Combination immunotherapies comprising IL-15 superagonists
    Patent number: 11020467
    Abstract: Methods and compositions for generating enhanced immune responses using adenovirus vectors that allow for multiple vaccinations in combination with an IL-15 superagonist complex in subjects in need thereof are provided.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: June 1, 2021
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Adrian Rice, Elizabeth Gabitzsch, Yvette Latchman, Joseph Balint
  • Compositions and methods for flavivirus vaccination
    Patent number: 10835596
    Abstract: Compositions of a recombinant adenovirus based vector vaccine containing one or more flavivirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate immune responses against flaviviruses are also described. Compositions described herein allow for vaccinations in subjects with preexisting immunity to adenovirus.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: November 17, 2020
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Joseph Balint, Adrian Rice, Yvette Latchman, Elizabeth Gabitzsch
  • Human adenovirus serotype 5 vectors containing E1 and E2B deletions encoding the ebola virus glycoprotein
    Patent number: 10695417
    Abstract: Methods for generating immune responses to Ebola virus antigens using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: June 30, 2020
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Elizabeth Gabitzsch
  • COMPOSITIONS AND METHODS FOR ALPHAVIRUS VACCINATION
    Publication number: 20200172925
    Abstract: Compositions of a recombinant adenovirus based vector vaccine containing one or more alphavirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate broad based immune responses against alphaviruses are also described. Compositions described herein allow for vaccinations in individuals with preexisting immunity to adenovirus.
    Type: Application
    Filed: July 14, 2017
    Publication date: June 4, 2020
    Applicant: ETUBICS CORPORATION
    Inventors: Frank R. JONES, Joseph BALINT, Adrian RICE, Yvette LATCHMAN, Elizabeth GABITZSCH
  • COMPOSITIONS AND METHODS FOR FLAVIVIRUS VACCINATION
    Publication number: 20200171140
    Abstract: Compositions of a recombinant adenovirus based vector vaccine containing one or more flavivirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate immune responses against flaviviruses are also described. Compositions described herein allow for vaccinations in subjects with preexisting immunity to adenovirus.
    Type: Application
    Filed: July 14, 2017
    Publication date: June 4, 2020
    Applicant: ETUBICS CORPORATION
    Inventors: Frank R. JONES, Joseph BALINT, Adrian RICE, Yvette LATCHMAN, Elizabeth GABITZSCH
  • Replication defective adenovirus vector in vaccination
    Patent number: 10563224
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: February 18, 2020
    Assignee: Etubics Corporation
    Inventors: Frank R. Jones, Elizabeth Gabitzsch
  • METHODS AND COMPOSITIONS FOR EBOLA VIRUS VACCINATION
    Publication number: 20170368161
    Abstract: Methods for generating immune responses to Ebola virus antigens using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Application
    Filed: January 7, 2016
    Publication date: December 28, 2017
    Applicant: Etubics Corporation
    Inventors: Frank R. Jones, Elizabeth Gabitzsch
  • Replication defective adenovirus vector in vaccination
    Patent number: 9605276
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 28, 2017
    Assignee: Etubics Corporation
    Inventors: Frank R Jones, Elizabeth Gabitzsch