Patents Assigned to Eurand America, Incorporated
  • Patent number: 5709886
    Abstract: Taste masked effervescent microcapsules are provided each microcapsule containing an effervescent admixture of sodium bicarbonate and citric acid microencapsulated with ethylcellulose, the effervescent microcapsules being useful in formulating taste masked effervescent chewable tablets also containing microencapsulated, unpleasant tasting drugs such as non-steroidal, anti-inflammatory, NSAID drugs.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: January 20, 1998
    Assignee: Eurand America, Incorporated
    Inventors: Marie Jean Bettman, Phillip J. Percel, Thomas C. Powell
  • Patent number: 5651984
    Abstract: A pharmaceutical dosage form is prepared from a multiplicity of coated potassium chloride crystals coated with two distinct layers, the first of ethylcellulose and the second of a hydrophilic coating polymer, preferably hydroxypropylcellulose, resulting in microcapsules. These microcapsules are capable of being compressed into tablets of suitable hardness and friability with minimum quantities of excipients. The resultant controlled release tablets are useful for treatment of potassium deficiencies in humans.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: July 29, 1997
    Assignee: Eurand America, Incorporated
    Inventor: Thomas Clark Powell
  • Patent number: 5639475
    Abstract: Taste masked effervescent microcapsules are provided each microcapsule containing an effervescent admixture of sodium bicarbonate and citric acid microencapsulated with ethylcellulose, the effervescent microcapsules being useful in formulating taste masked effervescent chewable tablets also containing microencapsulated, unpleasant tasting drugs such as non-steroidal, anti-inflammatory, NSAID drugs.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: June 17, 1997
    Assignee: Eurand America, Incorporated
    Inventors: Marie Jean Bettman, Phillip J. Percel, Thomas C. Powell
  • Patent number: 5622723
    Abstract: An improvement in the process of coacervation of chlorpheniramine maleate is provided whereby a predetermined amount of chlorpheniramine maleate charged to the process is maintained in the microcapsules by pre-saturating the coacervation medium with chlorpheniramine maleate.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: April 22, 1997
    Assignee: Eurand America, Incorporated
    Inventors: Marie J. Bettman, Sambasiva R. Ghanta
  • Patent number: 5422122
    Abstract: A pharmaceutical dosage form is prepared from a multiplicity of coated potassium chloride crystals coated with two distinct layers, the first of ethylcellulose and the second of a hydrophilic coating polymer, preferably hydroxypropylcellulose, resulting in microcapsules. These microcapsules are capable of being compressed into tablets of suitable hardness and friability with minimum quantities of excipients. The resultant controlled release tablets are useful for treatment of potassium deficiencies in humans.
    Type: Grant
    Filed: August 4, 1992
    Date of Patent: June 6, 1995
    Assignee: Eurand America, Incorporated
    Inventor: Thomas C. Powell
  • Patent number: 5071706
    Abstract: This disclosure is directed to the preparation of oily microcapsules which can be easily tray dried to a free flowing product without requiring special drying equipment. These microcapsules have a cell wall material having a first cell wall of gelatin/carboxymethylcellulose (CMC) which is prehardened (cross-linked) with a material selected from the group consisting of formaldehyde, glyoxal and glutaraldehyde to which there is grafted formaldehyde and urea. The predominant portion, viz., approximately 95% by wt. of these microcapsules have a particle size less than 1500 microns and more characteristically have a particle size ranging from about 100 to about 400 microns (microcapsular diameter). These microcapsules contain less than approximately 3 wt. % free oil and more characteristically less than about 1 wt. % free oil (non-microencapsulated oil) and have less free (unreacted) formaldehyde, which can be extracted with water, than do prior art microencapsulated oily materials.
    Type: Grant
    Filed: August 31, 1989
    Date of Patent: December 10, 1991
    Assignee: Eurand America, Incorporated
    Inventor: Jon C. Soper