Patents Assigned to Euro-Celtique, S.A.
  • Publication number: 20210085673
    Abstract: The present invention provides a method of providing pain relief in a human subject in need thereof comprising administering (R)-dihydroetorphine to said subject, wherein said (R)-dihydroetorphine is administered in a dose of at least 0.01 ?g/kg, preferably at least 0.05 ?g/kg, and the level of respiratory depression in said subject is 65 or less % relative to the baseline level pre-administration of (R)-dihydroetorphine.
    Type: Application
    Filed: September 30, 2020
    Publication date: March 25, 2021
    Applicant: EURO-CELTIQUE S.A.
    Inventors: John WATKINS, Alexander Oksche, Kevin Smith, Heikki Mansikka, Paul Bailey
  • Patent number: 10898479
    Abstract: The present invention provides a method of providing pain relief in a human subject in need thereof comprising administering (R)-dihydroetorphine to said subject, wherein said (R)-dihydroetorphine is administered in a dose of at least 0.01 ?g/kg, preferably at least 0.05 ?g/kg, and the level of respiratory depression in said subject is 65 or less % relative to the baseline level pre-administration of (R)-dihydroetorphine.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: January 26, 2021
    Assignee: Euro-Celtique S.A.
    Inventors: John Watkins, Alexander Oksche, Kevin Smith, Heikki Mansikka, Paul Bailey
  • Patent number: 10745406
    Abstract: The present invention provides a process for the preparation of a compound of formula (VI), or a salt or derivative thereof, wherein R1 and R2 are independently C1-8 alkyl and * represents a stereocentre.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: August 18, 2020
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Steve Whitelock, Deborah Phyllis Harding, Carl David Turner
  • Patent number: 10688258
    Abstract: Dispenser cap arrangements for enclosing a portion of a dispenser of a medicament are described herein.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: June 23, 2020
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Cathal Duignan, Peter Prior
  • Patent number: 10258616
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: April 16, 2019
    Assignee: Euro-Celtique S.A.
    Inventors: Helen Kathleen Danagher, Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Jonathon Oliver Whitehouse, Thinnayam Naganathan Krishnamurthy, Ricardo Alberto Vargas Rincon
  • Patent number: 10231936
    Abstract: Delivery of a drug is controlled to impart a delay before release after administration by formulating the drug with a disruption agent to provide a core, and coating the core with a regulatory membrane comprising a water-soluble gel-forming polymer and a water-insoluble film-forming polymer.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: March 19, 2019
    Assignee: Euro-Celtique S.A.
    Inventors: Derek Allan Prater, Mohammed Hassan, Christopher Robert Bland
  • Publication number: 20180344726
    Abstract: The present invention provides a transdermal delivery device comprising a pharmaceutical composition, wherein said composition comprises a N-oxide derivative of an opioid antagonist, or a salt thereof, and an opioid agonist or salt thereof.
    Type: Application
    Filed: November 18, 2016
    Publication date: December 6, 2018
    Applicant: EURO-CELTIQUE S.A.
    Inventor: Steve WHITELOCK
  • Patent number: 10071089
    Abstract: The present invention is concerned with an oral pharmaceutical dosage form comprising oxycodone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain in patients suffering from i) pain and at least one further disease ii), wherein said at least one further disease ii) results in intestinal dysbiosis, or for use in the treatment of pain in patients suffering from i) pain and at least one further disease iii), wherein said at least one further disease iii) increases the risk for intestinal bacterial translocation and thus for peritonitis, SIRS and/or sepsis.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: September 11, 2018
    Assignee: Euro-Celtique S.A.
    Inventors: Yvonne Von Coburg, Karen Reimer, Alexander Oksche, Peter Holzer
  • Publication number: 20180221299
    Abstract: The present invention provides a transdermal delivery system comprising (R)-dihydroetorphine, or a salt, hydrate or derivative thereof, wherein said system has a rapid onset of (R)-dihydroetorphine plasma concentration characterised by the mean in vivo plasma concentration of (R)-dihydroetorphine achieving at least 50% of its Cmax in less than 20 hours, preferably in less than 18 hours and more preferably in less than 12 hours, after application of the system to the skin of a human subject, e.g. when based on the mean plasma concentration versus time curve.
    Type: Application
    Filed: July 28, 2016
    Publication date: August 9, 2018
    Applicant: EURO-CELTIQUE S.A.
    Inventors: Steve WHITELOCK, Deborah Phyllis HARDING, Helen JOHNSON, Kevin SMITH, Gill MUNDIN
  • Publication number: 20180221298
    Abstract: The present invention provides a transdermal patch comprising: a drug-containing layer comprising (R)-dihydroetorphine, or a salt or a hydrate thereof, and a poly(meth)acrylate; and a backing layer.
    Type: Application
    Filed: July 28, 2016
    Publication date: August 9, 2018
    Applicant: Euro-Celtique S.A.
    Inventors: Steve WHITELOCK, Deborah Phyllis HARDING, Helen JOHNSON, Kevin SMITH, Gill MUNDIN
  • Patent number: 9993433
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human beings.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: June 12, 2018
    Assignee: Euro-Celtique S.A.
    Inventors: Geoffrey Gerard Hayes, Hassan Mohammad, Harjit Tamber, Malcolm Walden
  • Patent number: 9987441
    Abstract: A counter containing a first ring member having first indicia and a second ring member having second indicia, each of the first and second ring members being rotatable in increments about a common axis, one or both of the first and second indicia indicating a count; and a drive mechanism for rotating the first ring member and for rotating the second ring member after one or more predetermined degrees of rotation of the first ring member, wherein the drive mechanism contains a pawl-and-teeth mechanism which contains a first and second pawl engageable with a plurality of teeth, and wherein each of the first and second pawls contains a driving engagement face for engaging in a driving engagement with one of the plurality of teeth, and a sliding engagement face for sliding over one of the plurality of teeth.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: June 5, 2018
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Raymond Bacon, Iain Grierson McDerment
  • Patent number: 9901540
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human being.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: February 27, 2018
    Assignee: Euro-Celtique S.A.
    Inventors: Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Harjit Tamber
  • Patent number: 9814710
    Abstract: The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: November 14, 2017
    Assignee: Euro-Celtique S.A.
    Inventors: Helen Kathleen Danagher, Hassan Mohammad, Malcolm Walden, Geoffrey Gerard Hayes, Jonathon Oliver Whitehouse, Thinnayam Naganathan Krishnamurthy, Ricardo Alberto Vargas Rincon
  • Patent number: 9814679
    Abstract: The present invention provides a dosage form, particularly a tamper resistant dosage form, comprising: melt-extruded particulates comprising a drug; and a matrix; wherein said melt-extruded particulates are present as a discontinuous phase in said matrix.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 14, 2017
    Assignee: EURO-CELTIQUE S.A.
    Inventor: Hassan Mohammad
  • Patent number: 9805300
    Abstract: This invention generally relates to counters and in particular to counters for use with dispensers and to dispensers comprising said counters. More particularly the present invention relates to counters for use with metered-dose dispensers, such as metered-dose inhalers (MDIs). In particular, the present invention provides a counter comprising: a first ring member having a first indicia and being rotatable in increments about an axis, the first indicia indicating a count; a limiting member comprising a limiting mechanism, wherein the limiting mechanism comprises an engaging portion arranged to act radially with respect to the first ring member to contact the first ring member to limit free rotation of the first ring member relative to the limiting member about the axis.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: October 31, 2017
    Assignee: EURO-CELTIQUE S.A.
    Inventor: Cathal Duignan
  • Patent number: 9782359
    Abstract: The present invention relates to a composition, comprising (i) a matrix made of polymeric nanofibers, and (ii) an opioid agonist within the matrix.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: October 10, 2017
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Alexander Oksche, Kevin J. Smith, Derek Prater, Malcolm Walden, Will Heath, Bernard Kennedy, Vanessa Addison
  • Publication number: 20170267687
    Abstract: The present invention provides a process for the preparation of a compound of formula (VI), or a salt or derivative thereof, wherein R1 and R2 are independently C1-8 alkyl and * represents a stereocentre.
    Type: Application
    Filed: October 28, 2016
    Publication date: September 21, 2017
    Applicant: EURO-CELTIQUE S.A.
    Inventors: Steve WHITELOCK, Deborah Phyllis HARDING, Carl David TURNER
  • Patent number: 9764102
    Abstract: Dispenser cap arrangements for enclosing a portion of a dispenser of a medicament are described herein.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: September 19, 2017
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Cathal Duignan, Peter Prior
  • Patent number: RE47884
    Abstract: Dispensers, in particular dispensers for dispensing a dose of a gaseous, gas borne or droplet substance from a substance source and dispensers containing dosage counters are described herein.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: March 3, 2020
    Assignee: EURO-CELTIQUE S.A.
    Inventors: Cathal Duignan, Iain Grierson McDerment