Abstract: The present invention provides products having resveratrol with high water solubility and nutraceutical and/or phytotherapic compositions having said substances. The processes for obtaining them include the solubility increase of the polyphenol corresponding to a resveratrol compound, preferably trans-resveratrol in water, by its complexation with cyclodextrin under specific conditions that favor thermodynamic equilibrium. The products of the invention present high solubility and purity in aqueous medium, being, therefore, useful to prepare nutraceutical compositions (pharmaceutical and/or alimentary) with antioxidant, anti-inflammatory, antiviral, antidiabetics, cardioprotective, neuroprotective, chemoprotective activities; besides protecting against infections and ischemia, reducing obesity, and preventing aging.
Type:
Grant
Filed:
July 23, 2008
Date of Patent:
July 2, 2013
Assignees:
Uniao Brasileira de Educacao e Assistencia—Mantenedora da PUCRS, Eurofarma Laboratorios Ltda.
Abstract: The present invention refers to a process for obtaining a standardized extract having antinociceptive, anti-inflammatory and antipyretic properties, from at least one part of a plant of genus Aleurites. Furthermore, the present invention provides a pharmaceutical composition comprising an active ingredient of a pharmaceutically efficient quantity of standardized extract from at least one part of the plant of genus Aleurites. Finally, the present invention describes a method of treatment and use of the said extract, isolated or in a pharmaceutical composition, for the prevention, control or treatment of painful, inflammatory or febrile affections.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
March 26, 2013
Assignees:
Eurofarma Laboratorios Ltda, Fundaca O Universidade do Vale Do Itajai
Inventors:
Valdir Cechinel Filho, Tania Mari Belle Bresolim, Christiane Meire da Silva Bittencourt, Marcia Maria De Souza, Ruth Meri Lucinda, Nara Lins Meira Quintao, Ticiana Camila Mora, Carlos Picolli, Marcello Creado Pedreira, Marcelo Eidi Nita, Rodrigo Spricigo
Abstract: The present invention refers to a process for obtaining a standardized extract having antinociceptive, anti-inflammatory and antipyretic properties, from at least one part of a plant of genus Aleurites. Furthermore, the present invention provides a pharmaceutical composition comprising an active ingredient of a pharmaceutically efficient quantity of standardized extract from at least one part of the plant of genus Aleurites. Finally, the present invention describes a method of treatment and use of the said extract, isolated or in a pharmaceutical composition, for the prevention, control or treatment of painful, inflammatory or febrile affections.
Type:
Application
Filed:
October 24, 2008
Publication date:
December 2, 2010
Applicants:
EUROFARMA LABORATÓRIOS LTDA., FUNDACÃO UNIVERSIDADE DO VALE DO ITAJAÍ
Inventors:
Valdir Cechinel Filho, Tania Mari Belle Bresolim, Christiane Meire Bittencourt, Marcia Maria De Souza, Ruth Meri Lucinda, Nara Lins Meira Quintao, Ticiana Camila Mora, Carlos Picolli, Marcello Creado Pedreira, Marcelo Eidi Nita, Rodrigo Spricigo
Abstract: The present invention relates to a pharmaceutical composition comprising a combination of active principles. More specifically: a stable pharmaceutical composition comprising a combination of tramadol and ketoprofen. Furthermore, a combination in solid form in which the active principles are vehicled in pharmaceutical forms and/or products that prevent contact between them. Complementarily, the present invention also relates to the combined use of ketoprofen and tramadol in the preparation of an oral medicine useful for relieving pain as well as a method for relieving pain with an oral pharmaceutical composition comprising a combination of tramadol and ketoprofen.