Abstract: Provided is a method of treating female sexual dysfunction comprising administering a therapeutically effective amount of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, in free or pharmaceutically acceptable salt form, substantially free of the corresponding (?) enantiomer, to a female in need thereof.
Type:
Application
Filed:
November 11, 2014
Publication date:
September 29, 2016
Applicant:
Euthymics Bioscience, Inc.
Inventors:
Anthony Alexander MCKINNEY, Maurizio FAVA, Frank GENTILE
Abstract: The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms.